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双重抗血小板治疗对缺血性脑卒中患者的疗效 被引量:5

Effect of dual Antiplatelet Therapy in Patients with Ischemic Stroke
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摘要 目的探讨双重抗血小板治疗对缺血性脑卒中患者的疗效。方法选取我院2016年1月~2018年1月收治的缺血性脑卒中患者患者200例,计算机随机分成对照组与观察组,每组100例。对照组患者接受溶栓治疗,观察组患者在对照组溶栓治疗的基础上接受双重抗血小板治疗。比较两组患者临床疗效、神经功能缺损程度、凝血指标。结果观察组患者临床总有效率显著高于对照组,临床疗效比较有差异(P<0.05)。用药前两组患者神经功能缺损程度差异比较无统计学意义(P>0.05),治疗后观察组患者轻度缺损率显著高于对照组(P<0.05),两组神经功能缺损程度差异比较有统计学意义(P<0.05)。治疗前患者PLT、aPTT、PT、TT、Fbg比较无差异(P>0.05),治疗后观察组患者PLT、Fbg水平下调(P<0.05),aPTT、PT、TT上调(P>0.05)。结论双重抗血小板是治疗缺血性脑卒中有效方法,能显著提高疗效,改善神经功能,值得推荐。
作者 师宁 董治燕 李海军 高晓嵘 SHI Ning;DONG Zhi-yan;LI Hai-jun;GAO Xiao-rong(Department of Neurology,Affiliated Hospital of Yan'an University,Yan'an,716000,China)
出处 《血栓与止血学》 2019年第3期439-440,443,共3页 Chinese Journal of Thrombosis and Hemostasis
基金 延安市科技项目(2016 KS-03)
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