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利拉鲁肽对2型糖尿病合并脑血栓患者高敏C反应蛋白和血脂及颈动脉粥样硬化斑块的影响探究 被引量:16

Effects of Liraglutide on Sensitivity C-reactive Proteinand Blood Lipids and Carotid Atherosclerotic Plaque in Patients with Type 2 Diabetes Mellitus Complicated with Cerebral Thrombosis
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摘要 目的探讨利拉鲁肽对2型糖尿病合并脑血栓患者高敏C反应蛋白(hs-CRP)和血脂及颈动脉粥样硬化斑块的影响。方法选择2016年1月至2018年9月我院收治的110例2型糖尿病合并脑血栓患者,随机分为两组,各55例。对照组采取二甲双胍治疗,观察组采取二甲双胍联合利拉鲁肽治疗。比较两组高敏C反应蛋白(hs-CRP)、血脂水平、血糖水平及斑块变化情况。结果治疗后,观察组hs-CRP、LDL、TG及TC低于对照组,HDL高于对照组,观察组血糖水平低于对照组,观察组颈动脉粥样硬化斑块面积及动脉内膜中层厚度均小于对照组,差异具有统计学意义(P<0.05)。结论 2型糖尿病合并脑血栓患者采取利拉鲁肽治疗,可有效改善患者hs-CRP及血脂水平,降低血糖水平,缩小斑块面积及中层厚度,促进患者康复。
作者 崔红 赵龙 张颖 于晶 CUI Hong;Zhao Long;ZHANG Ying;YU Jing(Department of Pharmacy, Red Flag Hospital affiliated to Mudanjiang Medical College, Mudanjiang, 157000, China)
出处 《血栓与止血学》 2019年第3期441-443,共3页 Chinese Journal of Thrombosis and Hemostasis
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