参术调中汤治疗老年肺炎对免疫功能的影响

Influence of ShenZhu Tiaozhong Decoction on the Curative Effect and Immune Function o f Elderly Patients with Pneumonia

目的:探讨参术调中汤对老年肺炎患者的疗效及免疫功能的影响。方法:90例老年肺炎患者随机分为观察组和对照组,每组45例。对照组采取常规治疗措施,观察组在对照组基础上给予参术调中汤治疗。治疗2个疗程后,比较2组疗效和免疫功能。结果:治疗后,观察组患者症状、体征消失时间及平均住院时间明显优于对照组,两组比较差异有统计学意义(P<0.05)。治疗后,观察组患者的并发症发生率明显低于对照组,两组比较差异有统计学意义(P<0.05)。治疗后两组患者IL-2、IL-10均明显升高、TNF-α明显降低,2组间比较差异有统计学意义(P<0.05)。结论:参术调中汤治疗老年肺炎患者疗效显著,能有效调节机体免疫功能,值得在临床推广应用。

Objective To investigate the influence of Shen Zhu Tiaozhong decoction on the curative effect and immune function of elderly patients with pneumonia. Methods 90 cases of pneumonia in our hospital were selected as research subjects from February 2017 to March 2018.According to the random number table method, the patients were randomly divided into the observation group and the control group, 45 cases in each group.The control group received routine treatment and the observation group was given Shen Zhu Tiaozhong decoction on the basis of the control group. The symptoms, signs disappearance time, average hospitalization time, complications, inflammatory function were evaluated. Results After treatment, the symptoms, signs disappearance time and average hospitalization time of the observation group were significantly better than those of the control group ( P<0.05 ).After treatment, the incidence of complications in the observation group was significantly lower than that in the control group ( P<0.05 ).Compared with before treatment, the levels of IL-2、IL-10 in the two groups were significantly higher and TNF- a was significantly lower ( P<0.05 ), and there was no significant difference between the two groups ( P>0.05 ). After treatment, the levels of IL-2、IL-10 in the observation group were significantly higher than those in the control group, and TNF- a was significantly lower than those in the control group ( P<0.05 ). Conclusion Shen Zhu Tiaozhong decoction is effective in the treatment of senile pneumonia, and can effectively regulate the immune function of the body, which is worthy of clinical application.