2008-2017年吉林省丙型病毒性肝炎流行病学特征

Epidemiological characteristics of viral hepatitis C in Jilin Province, 2008-2017

目的描述2008-2017年吉林省丙型病毒性肝炎的流行病学特征,探讨吉林省丙型病毒性肝炎的发病变化趋势,为防控工作提供科学依据。方法使用中国疾病预防控制信息系统监测数据,采用描述流行病学方法分析2008-2017年吉林省丙型病毒性肝炎疫情情况。结果2008-2017年吉林省丙型病毒性肝炎发病率从2008年的21.18/10万,上升到2011年的33.06/10万,2012年以后逐年下降。十年间报告发病数最多的是松原市,年均发病率最高的是延边州(47.12/10万)。男女性别比1.23∶1。40岁以上病例占总发病数的91.25%。病例中农民所占比例最多(38.06%)。结论2012年以后吉林省丙肝报告发病率呈下降趋势。目前口服直接抗病毒药物已在中国上市,应加强在丙肝高流行地区的救治工作,切实提高丙肝患者治愈率。

Objective To describe the epidemiological features of viral hepatitis C in Jilin Province from 2008 to 2017,to explore the changing trend of incidence of viral hepatitis C in Jilin Province,and to provide a scientific basis for its prevention and control. Methods We made a descriptive epidemiological analysis of viral hepatitis C in Jilin Province during 2008-2017 based on the surveillance data from China Disease Prevention and Control Information System.Results The incidence rate of viral hepatitis C in Jilin Province during 2008-2017 increased from 21.18/100,000 in 2008 to 33.06/100,000 in 2011, and then decreased year by year since 2012. The number of cases reported in Songyuan City was the largest, and the average annual incidence rate in Yanbian City was found to be the highest (47.12/100,000). The male-to-female ratio was 1.23∶1. 91.25% of the patients were 40 years old and above. Farmers accounted for the largest proportion of the patients (38.06%).Conclusions The reported incidence rate of hepatitis C in Jilin Province showed a downward trend since 2012. Oral direct-acting antiviral agents(DAA) have now been put on the market in China. Medical resources should be actively coordinated to carry out treatment work in areas with high prevalence of hepatitis C so as to effectively improve the cure rate of hepatitis C.