用药错误预防及管理临床实践指南的质量评价与内容分析

Quality appraisal and content analysis of clinical practice guidelines on prevention and management of medication errors

目的评价用药错误预防及管理相关临床实践指南,为减少临床用药错误、提高护士给药安全提供参考。方法计算机检索指南发布主要网站、专业学会网站和电子文献数据库,检索时限为建库至2019年1月31日,应用临床指南研究与评价工具Ⅱ(Appraisal of Guidelines for Research EvaluationⅡ,AGREEⅡ)评价循证指南,采用澳大利亚JBI循证卫生保健中心专家共识评价标准(2017)对基于专家共识的指南进行评价,并总结分析各指南的推荐内容。结果共纳入10部临床实践指南,其中循证指南4部,基于专家共识的指南6部;1部循证指南的总体质量评价为A级,3部为B级,指南整体质量较高。纳入的6部专家共识指南总体评价结果均为“纳入”。从10部指南共提取27条关于给药错误预防和管理的推荐意见。结论纳入的用药错误预防及管理临床实践指南质量整体较高,其推荐意见可为进一步规范临床用药,提高临床用药安全提供依据。

Objective To evaluate the quality of clinical practice guidelines concerning prevention and manage ment of medication errors, to provide recommendations for reducing medication errors improving medication safety among nurses.Methods The included guidelines recruited from international guideline websites, websites of academ ic societies or institutions,and electronic databases (from inception to January 31st 2019)were evaluated and ana lyzed.Results Ten guidelines were included.Four of them were evidence-based and the other six were expert consensus.One evidence-based guideline was rated according to AGREE II as A, three were rated as B,and the quality was relatively high.All 6 expert consensus guidelines were rated as included.Totally 27 items of recom mendation were summarized from 10 guidelines.Conclusion The quality of the included guidelines for prevention and management of medication errors is good in general.Recommendations can offer evidence for regulated medi cation,and improve safety of medication.