MRI诊断急性脑梗死的价值及梗死病灶ADC值的变化

Diagnostic value of MRI in patients with acute cerebral infarction and the changes in apparent diffusion coefficient of infarct lesions

目的:探讨磁共振成像(MRI)在急性脑梗死诊断中的应用价值。方法:选取2017年1月~2018年6月在柳州市中医医院治疗的急性脑梗死患者92例,均给予CT、MRI检查,同时测量梗死病灶和对侧正常脑组织表观弥散系数(ADC)值。结果:MRI脑梗死检出率为96.74%,明显高于CT检查(P<0.05);发病至入院时间<24 h、24~72 h患者MRI检出率分别为93.10%和97.06%,明显高于CT检查(P<0.05);发病至入院时间>72 h患者MRI和CT检出率比较差异无统计学意义(P>0.05);发病至入院时间<24 h、24~72 h、>72 h患者梗死病灶ADC值分别为(4.47±1.23)×10^-4、(4.68±1.30)×10^-4、(6.02±1.53)×10^-4mm^2/s,明显低于对侧脑组织(P<0.05)。结论:MRI在急性脑梗死诊断中有较好的应用价值,其中ADC值可为判断梗死病灶部位提供客观依据。

Objective To explore the application value of magnetic resonance imaging(MRI) in the diagnosis of acute cerebral infarction. Methods Ninety-two patients with acute cerebral infarction treated in Liuzhou Hospital of Traditional Chinese Medicine from January 2017 to June 2018 were examined by CT and MRI, and the apparent diffusion coefficient(ADC) of infarct lesions and contralateral normal brain tissues were measured. Results The detection rate of cerebral infarction on MRI was 96.74%,which was significantly higher than that on CT(P<0.05). The detection rates of MRI in patients with different durations from onset of symptoms to admission(<24 h and 24-72 h) were 93.10% and 97.06%, respectively, which were significantly higher than those of CT(P<0.05). There was no significant difference in the detection rate between MRI and CT in patients with >72 h duration from onset of symptoms to admission(P>0.05). The ADC of infarct lesions in patients with different durations from onset of symptoms to admission(<24 h, 24-72 h and >72 h) were(4.47±1.23)×10^-4,(4.68±1.30)×10^-4 and(6.02±1.53)×10^-4 mm^2/s,respectively, which were significantly lower than those of contralateral brain tissues(P<0.05). Conclusion MRI has good application values in the diagnosis of acute cerebral infarction. Moreover, ADC can provide objective basis for determining the locations of infarct lesions.