不同介入治疗时间对急性心肌梗死患者左室舒张功能的影响分析

Effect of different intervening time on left ventricular diastolic function in patients with acute myocardial infarction

目的分析急性心肌梗死患者经不同时间介入治疗对其左室舒张功能的影响。方法2017年9月~2018年11月期间,选取收治的急性心肌梗死患者85例为研究对象,根据介入治疗时间的不同分为对照组(择期治疗,44例)和观察组(急诊治疗,41例)。对比两组患者左心室射血分数、脑钠肽水平以及心脏不良事件发生情况。结果观察组的脑钠肽水平(1014.61±20.36)ng/L、心脏事件总发生率(2.44%)显著低于对照组的脑钠肽水平(1804.23±21.50)ng/L、心脏事件总发生率(22.73%);观察组的左心室射血分数(59.40±3.40)%显著高于对照组的左心室射血分数(51.08±3.74)%,差异具有统计学意义(P<0.05)。结论急诊经皮冠状动脉内介入治疗效果显著,能够有效降低脑钠肽水平,避免心衰等心脏不良事件的发生,提高左心室射血分数,改善预后。

Objective To analyzed the effect of interventional therapy at different time on left ventricular diastolic function in patients with acute myocardial infarction. Methods From September 2017 to November 2018, 85 patients with acute myocardial infarction in our hospital were selected as the study subjects. According to the time of interventional therapy, they were divided into control group( selective treatment, 44 cases) and observation group (emergency treatment, 41 cases). The left ventricular ejection fraction, brain natriuretic peptide level and adverse cardiac events were compared between the two groups. Results The levels of brain natriuretic peptide( 1 014.61±20.36) ng/L and the total incidence of cardiac events( 2.44%) in the observation group were significantly lower than those in the control group( 1 804.23±21.50) ng/L and the total incidence of cardiac events( 22.73%). The left ventricular ejection fraction( 59.40±3.40)% in the observation group was significantly higher than that in the control group( 51.08±3.74)%. The difference was statistically significant( P < 0.05). Conclusion Emergency percutaneous coronary intervention can effectively reduce the level of brain natriuretic peptide, avoid adverse cardiac events such as heart failure, improve left ventricular ejection fraction and improve prognosis.