气管抽吸标本微生物检测在预测新生儿呼吸机相关性肺炎中的作用分析

Analysis of the Role of Microbial Detection in Tracheal Aspiration Specimens in Predicting Ventilator-associated Pneumonia in Newborns

目的探讨气管抽吸标本微生物检测在预测新生儿呼吸机相关性肺炎中的作用。方法选取2016年6月-2018年10月收治的92例重症监护病房患儿作为研究对象,将其分为观察组与对照组,每组各46例。结果两组患儿在性别、入院体温、白细胞计数、CRP、PCT、ALT对比(P>0.05);两组患儿在胎龄、出生体质量、机械通气时间对比(P<0.05)。观察组中革兰阴性菌以鲍曼不动杆菌占比最高,革兰阳性菌中以金黄色葡萄球菌占比最高,真菌中以白假丝酵母菌占比最高。观察组重症监护病房住院时间、总住院时间长于对照组,而病死率高于对照组(P<0.05)。结论气管抽吸标本微生物检测用于预测新生儿是否患有呼吸机相关性肺炎具有较高的临床价值。

Objective To explore the role of microbial detection in predicting ventilator-associated pneumonia in neonates. Methods 92 children in ICU from June 2016 to October 2018 were selected as the study subjects. They were divided into observation group and control group with 46 cases in each group. Results The two groups were compared in sex, admission temperature, white blood cell count, CRP, PCT and ALT (P > 0.05). The gestational age, birth weight and mechanical ventilation time of the two groups were compared(P < 0.05). In the observation group, Acinetobacter baumannii accounted for the highest proportion of gram-negative bacteria, Staphylococcus aureus accounted for the highest proportion of Gram-positive bacteria and Candida albicans accounted for the highest proportion of fungi. The hospitalization time and total hospitalization time of the observation group were longer than those of the control group, and the mortality rate was higher than that of the control group(P < 0.05). Conclusion Microbial detection of tracheal aspiration specimens has high clinical value in predicting whether newborns suffer from ventilator-associated pneumonia.