CCRT改善VD认知功能及生活质量的研究

The Effect of Computer-assisted Cognitive Remediation Therapy on Cognitive Function and Social Function of Patients With Vascular Dementia

目的探讨计算机认知矫正治疗(computer-assisted cognitive remediation therapy,CCRT)改善血管性痴呆(vascular dementia,VD)患者认知功能和社会功能及生活质量的作用。方法98例2017年1月-2018年1月我院收治的VD患者进行CCRT治疗,治疗前后应用简易智力状态检查量表(MMSE)、社会功能缺陷筛选量表(SDSS)、个人和社会功能量表(PSP)、生活质量综合评定(GQOL-74)量表进行评估。结果(1)与治疗前比,治疗后的定向力(5.60±1.35)分、计算力(2.20±0.79)分、语言能力(7.10±0.36)分、空间能力(0.78±0.24)分、即刻记忆力(2.42±0.53)分、短程记忆力(1.17±0.78)分及MMSE总分(23.36±2.98)分均所有提高(P<0.05);(2)与治疗前比较,治疗后SDSS、PSP、ADL评分(8.23±0.94)分、(81.36±14.23)分、(32.7±12.1)分均有所改善(P<0.05);(3)与治疗前比较,治疗后躯体健康(68.24±7.44)分、心理健康(69.75±7.15)分、社会功能(69.08±7.43)分、物质生活(37.46±4.85)分及总分(230.79±9.56)分均有所提升(P<0.05)。结论血管性痴呆患者应用CCRT系统治疗,能有效改善认知功能、社会功能及日常生活能力,提高生活质量。

Objective To analyze the effects of computer-assisted cognitive remediation therapy on cognitive function and social function in patients with vascular dementia. Methods The clinical data of 98 patients with VD who had received treatment in the hospital from January 2017 to January 2018 were selected. CCRT systematic treatment was carried out on all of the patients. The cognitive function, social function and quality of life of the patients before and after treatment were observed. Results (1) Compared with before treatment, the scores of orientation(5.60±1.35) points, calculating power(2.20±0.79) points, language ability(7.10±0.36) points, spatial ability(0.78±0.24) points, immediate memory(2.42±0.53) points, short-term memory(1.17±0.78) points and MMSE(23.36±2.98) points were all improved after treatment(P<0.05).(2) Compared with those before treatment, the scores of SDSS, PSP and ADL(8.23±0.94) points,(81.36±14.23) points and(32.7±12.1) points were improved after treatment(P<0.05).(3) Compared with those before treatment, the scores of physical health(68.24±7.44) points, mental health(69.75±7.15) points, social function(69.08±7.43) points, material life(37.46±4.85) points and total score(230.79±9.56) points increased after treatment(P<0.05). Conclusion For patients with vascular dementia, CCRT can help improve their cognitive function, social function and quality of life.