吸烟行为与心血管病监测指标相关性分析

Correlation between smoking behavior and cardiovascular disease risk indicators

目的分析湖北省35~75岁男性居民吸烟行为及其与心血管病监测指标的相关性。方法2015—2016年采用单因素方差进行分析比较23453名居民不同吸烟行为的心血管病监测指标,用趋势检验探讨其相关性。结果农村重度吸烟者高于城市达到28.07%;以45~年龄组重度吸烟比例最高(31.31%);学历越低重度吸烟比例越高,文盲构成比为29.37%。常吸烟者的体质指数、腰围、空腹血糖、平均收缩压均数比从未吸烟者低,戒烟者均数比从未吸烟者高,有统计学意义(P<0.05)。从未吸烟者总胆固醇均数与其他吸烟行为均有统计学差异(P<0.05)。戒烟者总胆固醇水平与戒烟年数不存在线性趋势(P>0.05)。结论吸烟行为和戒烟行为对体质指数、腰围、空腹血糖、平均收缩压存在双向影响,戒烟行为存在矫枉过正;吸烟行为导致的总胆固醇水平改变是不可逆的。

Objective To analyze of the correlation between smoking behavior and prevalence of risk factors for cardiovascular disease (CVD) among male residents aged 35 to 75 years in Hubei province.Methods We extracted surveillance data on 23 453 residents aged 35-75 years collected between 2015-2016 in 2 urban and 4 rural regions of Hubei province covered by national project for screening and comprehensive intervention in populations at high CVD risk. One-way analysis of variance and correlation trend test were adopted to explore the association of smoking behavior with the prevalence of CVD risk factors among the participants.Results The rural participants had a higher proportion (28.07%) of heavy smoking than the urban residents and the participants aged 45-54 years had the highest proportion (31.31%) of heavy smoking. A reverse correlation between education level and heavy smoking was observed and the proportion of heavy smoking was 29.37% among the illiterate participants. Among the participants, the means of body mass index, waist circumference, fasting blood glucose, and average systolic pressure were lower in regular smokers than in the never smokers and all the means were higher in ex-smokers than in never smokers significantly (P < 0.05). The average total cholesterol (TC) of the never smokers was statistically different from that of other participants (P < 0.05). No significant linear correlation between TC and number of years of smoking cessation was observed among the ex-smokers (P > 0.05).Conclusion Smoking and smoking cessation have bidirectional effects on body mass index, waist circumference, fasting blood glucose, and mean systolic blood pressure and smoking cessation has over-correction effect on the four indicators. Smoking induced variation in total cholesterol level may be irreversible.