福州地区献血人群丙型肝炎病毒感染情况的评估

Prevalence study of hepatitis C virus infection in blood donors in Fuzhou areas

目的评估福州地区无偿献血人群HCV感染情况。方法参照中国疾病预防控制中心2011年发布《丙型肝炎病毒实验室检测技术规范》中的抗-HCV检测疫情报告流程,以2种不同厂家ELISA试剂均为反应性为阳性判断标准,分析2006—2011年及2016—2017年福州地区献血者抗-HCV检测结果。结果8年间共检测619 838份献血者血液样本,检出HCV阳性样本208份(0.034%)。2种ELISA试剂筛查不同年份的总反应性率范围在0.209%~0.331%,均值为0.260%。按照CDC推荐流程判定不同年份抗-HCV阳性率分别为0.038%、0.026%、0.032%、0.034%、0.046%、0.038%、0.039%和0.015%,均值为0.034%。结论福州地区无偿献血人群HCV感染率处于非常低的水平。

Objective To assess the HCV infection among the blood donors in Fuzhou. Methods Anti-HCV testing results by two different ELISA kits were retrospectively analyzed according to Specification Procedure of HCV Testing in Laboratory published by Chinese Center for Disease Control and Prevention in 2011. Positive reactivity of the both kits was considered as the criterion, and the prevalence of HCV-infected blood donors was evaluated during 2006-2011 and 2016-2017 in Fuzhou. Results A total of 619 838 serum samples from blood donors were tested during the eight years, among which 208 (0.034%) samples were HCV-positive. The range of the annual anti-HCV reactivity rates were from 0.209% to 0.331%, with the average of 0.260%. According to the regulation by Chinese Center for Disease Control and Prevention, the annual anti-HCV positive rates were 0.038%, 0.026%, 0.032%, 0.034%, 0.046%, 0.038%, 0.039% and 0.015% respectively, and the mean positive rate was 0.034%. Conclusions HCV prevalence is very low among blood donors in Fuzhou areas.