原发性透明细胞型肝癌患者应用磁共振成像诊断的效果及其临床价值分析

Clinical value analysis of magnetic resonance imaging in diagnosis of primary clear cell hepatocellular carcinoma

目的:探究原发性透明细胞型肝癌患者应用磁共振成像(MRI)诊断的效果及其临床价值。方法:回顾性选取在医院治疗的28例原发性透明细胞型肝癌患者,将其分为观察组和对照组,每组14例;观察组采用MRI进行检查,对照组采用X射线计算机断层扫描(CT)检查,比较两组病灶检查状况、误诊率及影像表现等。结果:观察组MRI检出的病灶数量、椭圆病灶和类圆病灶均高于对照组的CT检查,其差异有统计学意义(x2=6.825,x2=5.429,x2=6.317;P<0.05)。对照组CT检查血管平滑肌脂肪瘤、炎性假瘤、肝血管瘤和再生结节占比和误诊率分别为28.6%、21.4%、21.4%、7.1%和78.6%,均高于观察组MRI检查的7.1%、7.1%、0.0%、0.0%和14.3%,其差异有统计学意义(x2=6.752,x2=5.041,x2=5.204,x2=3.874,x2=7.518;P<0.05);观察组MRI图像检测出的腹腔积液和后腹膜淋巴结肿大均明显多于对照组CT图像检测,其差异有统计学意义(x2=5.704,x2=4.039,P<0.05),而观察组MRI图像检测的边缘不清例数显著少于对照组CT图像检测,差异有统计学意义(x2=5.271,P<0.05)。结论:MRI在诊断原发性透明细胞型肝癌方面效果显著,有利于临床疾病的确诊,具有一定的临床应用价值。

Objective: To investigate the effect and clinical value of magnetic resonance imaging (MRI) diagnosis for patients with hepatocellular carcinoma of primary transparent cell type. Methods: Twenty-eight patients with hepatocellular carcinoma of primary transparent cell type who were treated in the hospital were retrospectively selected. And these patients who underwent MRI were divided into the observation group (14 cases), and other 14 patients who underwent computed tomography (CT) examination were divided into control group. The lesion status, misdiagnosis rate and image performance of the two examination methods were compared. Results: The elliptical lesions, the round-like lesions and the number of lesions that were detected by MRI were significantly higher than those by CT (x2=6.825, x2=5.429, x2=6.317, P<0.05). The lipomyoma of vascular smooth muscle, inflammatory pseudotumor, hepatic hemangioma, node of regeneration and misdiagnosis rate of CT examination in control group were respectively 28.6%, 21.4%, 21.4%, 7.1% and 78.6%, and they were significantly higher than those of MRI examination in observation group (7.1%, 7.1%, 0.0%, 0.0% and 14.3%)(x2=6.752, x2=5.041, x2=5.204, x2=3.874, x2=7.518, P<0.05). The seroperitoneum and lymphadenectasis of posterior peritoneum that were confirmed by MRI in observation group were significantly more than those that were confirmed by CT in control group (x2=5.704, x2=4.039, P<0.05). And the number of ambiguous margin that was detected by MRI in observation group was significantly less than that was detected by CT in control group (x2=5.271, P<0.05). Conclusion: MRI is effective in diagnosing hepatocellular carcinoma of primary transparent cell type, which is conducive to the diagnosis of clinical diseases. And it has certain clinical application value.