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CRP、PTX-3联合CPIS在呼吸机相关性肺炎中的研究 被引量:5

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摘要 目的通过探讨C-反应蛋白(CRP)、穿透素-3(PTX-3)联合临床肺部感染评分(CPIS)在呼吸机相关性肺炎中的价值,以期为临床呼吸机相关性肺炎的诊断和治疗提供临床依据。方法选取300例入住湖北省宜昌市妇幼保健院确诊为呼吸机相关性肺炎患者和同期入住该院的225例机械通气未感染者作为呼吸机相关性肺炎组和对照组,比较两组患者血清CRP、PTX-3水平和CPIS评分,绘制受试者工作特征曲线(ROC曲线)分析CRP、PTX-3水平和CPIS对呼吸机相关性肺炎患者的诊断价值。结果呼吸机相关性肺炎组患者血清CRP、PTX-3水平和CPIS评分均明显高于对照组(P<0.05)。ROC曲线分析显示,CRP、PTX-3水平和CPIS评分的ROC曲线下面积分别为0.91、0.89和0.95,诊断灵敏度分别为87.6%、80.6%和83.6%,特异度分别为70.5%、82.5%和72.5%。结论CRP、PTX-3水平联合CPIS评分对呼吸机相关性肺炎有较高诊断价值,可提高呼吸机相关性肺炎诊断的灵敏度和特异度,具有一定的临床应用价值。
作者 熊英 马芹
出处 《国际检验医学杂志》 CAS 2019年第13期1630-1633,共4页 International Journal of Laboratory Medicine
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