酚妥拉明联合蛇毒血凝酶治疗肺结核并发咯血疗效分析

Phentolamine combined with snake venom hemocoagulase in the treatment of pulmonary tuberculosis complicated with hemoptysis

目的对酚妥拉明联合蛇毒血凝酶治疗肺结核并发咯血的临床疗效进行探讨。方法选择2017年1月~2018年12月我院接受治疗肺结核并发咯血患者50例,随机将患者分为实验组(n=25)和常规组(n=25)。常规组患者采用持续静脉泵入脑垂体后叶素治疗,实验组患者采用静脉滴注酚妥拉明和蛇毒凝血酶治疗,观察并比较两组患者疗效。结果实验组患者治疗总有效率92.0%,显著高于常规组的72.0%,差异有统计学意义(P<0.05)。实验组患者不良反应发生率8.0%,显著低于常规组的60.0%,差异有统计学意义(P<0.05)。结论在肺结核合并咯血患者中该应用酚妥拉明联合蛇毒血凝酶治疗效果显著,并且副作用较少,值得进行广泛推广。

Objective To investigate the clinical efficacy of phentolamine combined with snake venom hemocoagulase in the treatment of pulmonary tuberculosis complicated with hemoptysis.Methods 50 patients with pulmonary tuberculosis complicated with hemoptysis were selected,all patients were treated in our hospital from January 2017 to December 2018,they were randomly divided into experimental group (n=25) and conventional group (n=25).The conventional group was treated with continuous intravenous infusion of pituitrin, while the experimental group was treated with intravenous infusion of phentolamine and snake venom thrombin.Results The total effective rate of the experimental group was 92.0%,significantly higher than 72.0% of the conventional group (P<0.05). The incidence of adverse reactions in the experimental group was 8.0%,which was significantly lower than 60.0% in the conventional group (P<0.05).Conclusion Phentolamine combined with snake venom hemocoagulase is effective in the treatment of pulmonary tuberculosis patients with hemoptysis, and has fewer side effects,it is worth popularizing widely.