住院老年精神病患者传染病原体感染及免疫功能研究

Study on infectious pathogen infection and immune function in hospitalized elderly patients with mental illness

目的研究住院老年精神病患者的传染病原体感染状况和其机体免疫功能情况。方法选取2016年2月至2018年6月本院收治的200例老年精神病患者,检测患者的传染病原体感染状况,并对比传染病原体感染者和传染病原体非感染者的免疫功能指标。结果200例老年精神病患者中,传染病原体感染者占据5.00%,其中,单一感染类型占据60.00%,混合感染类型占据40.00%;乙型肝炎病毒感染总计率最高,占据3.00%,之后分别为梅毒螺旋体、丙型肝炎病毒、人类免疫缺陷病毒,分别占据2.00%、1.50%、0.50%;传染病原体感染者的免疫球蛋白A检测值、免疫球蛋白G检测值、免疫球蛋白M检测值、补体C3检测值、补体C4检测值对比传染病原体非感染者对应指标均降低,差异具有统计学意义。结论住院老年精神病患者的传染病原体感染以乙型肝炎病毒为主,混合感染类型以乙型肝炎病毒+梅毒螺旋体为主,传染病原体感染者的机体免疫功能指标降低。

Objective To study the infection status of infectious pathogens and their immune function in hospitalized elderly patients with mental illness. Methods The data studied in this paper were obtained from 200 elderly patients with mental illness admitted to the hospital. The case study time was from February 2016 to June 2018, the infection status of the infected patients was detected and compared with those infected with infectious agents. And immune function indicators of non-infected persons with infectious pathogens. Results Among 200 elderly patients with mental illness, infectious disease infected persons accounted for 5.00%, of which, single infection type accounted for 60.00%, mixed infection type occupied 40.00%;hepatitis B virus infection rate was the highest, accounting for 3.00%, followed by syphilis Spirulina, Hepatitis C virus, and human immunodeficiency virus account for 2.00%, 1.50%, and 0.50%, respectively;immunoglobulin A detection value, immunoglobulin G detection value, immunoglobulin M detection value, complement of infected pathogens. The C3 detection value and complement C4 detection value were lower than those of non-infected patients with infectious pathogens (P<0.05), and there were statistical significance of index research and comparison. Conclusion The infectious pathogens of hospitalized elderly patients with psychiatric diseases are mainly hepatitis B virus. The mixed infection type is mainly hepatitis B virus + syphilis, and the immune function index of infected pathogens is reduced.