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联合检测食管癌手术患者CTCs、CEA、Scc和CA199的临床意义 被引量:6

Clinical significance of combined detection of CTCs, CEA, Scc and CA199 in patients undergoing esophageal cancer surgery
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摘要 目的探讨联合检测循CTCs、CEA、Scc、CA199在食管癌手术患者中的临床意义。方法选择行食管癌根治手术患者112例,检测患者外周血CTCs、CEA、Scc、CA199在术前和术中含量,比较术前术后上述指标变化,并进行统计学分析。结果检测患者外周血CTCs、CEA、Scc、CA199的含量,手术前较手术后含量高;Ⅲ期的患者上述指标含量最高,而Ⅰ期和Ⅱ期的患者上述指标含量差异无统计学意义;随访2年,术后出现肿瘤复发及转移患者29例,其外周血CTCs、CEA、Scc、CA199的含量明显高于未出现肿瘤复发患者;联合检测CTCs、CEA、Scc、CA199的含量对于评估食管癌术后复发和转移的准确率高于单一指标检测。结论联合检测CTCs、CEA、Scc、CA199的含量对于食管癌早期诊断与评估分期有一定价值,对诊断术后复发和转移的准确率高于单一指标检测。
作者 张胜强 崔虎军 郭建宇 李荣辉 徐明鑫 齐宝林 张洪艳 Zhang Shengqiang;Cui Hujun;Guo Jianyu
出处 《当代医学》 2019年第20期118-119,共2页 Contemporary Medicine
基金 牡丹江市科学技术计划项目(Z2016s0078)
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