摘要
目的探讨冻干重组人脑利钠肽(商品名:新活素)对老年心力衰竭患者尿量及精神状态的意义。方法80例老年心力衰竭患者,随机分为试验组和对照组,每组40例。对照组采取常规抗心力衰竭西医治疗及对症支持治疗,试验组在对照组的基础上使用新活素进行治疗。观察并比较两组患者治疗后焦虑自评量表(SAS)、抑郁自评量表(SDS)评分及24h尿量。结果治疗后,试验组SAS、SDS评分分别为(41.68±5.37)、(16.98±4.37)分,均低于对照组的(50.99±6.45)、(23.45±5.97)分,差异具有统计学意义(P<0.05);试验组24h尿量为(1234.98±80.35)ml/24h,少于对照组的(1567.78±73.81)ml/24h,差异具有统计学意义(P<0.05)。结论使用新活素对老年心力衰竭患者进行治疗,可以明显改善心力衰竭患者24h尿量,改善患者的精神状态,提高患者生活质量,值得在临床推广。
Objective To discuss the significance of (lyophilized recombinant human brain natriuretic peptide (trade name:Xinhuosu) on urine volume and mental state in elderly patients with heart failure.Methods A total of 80 elderly patients with heart failure were randomly divided into experimental group and control group, with 40 cases in each group.The control group was treated with routine anti-heart failure Western medicine and symptomatic supportive treatment,and the experimental group was treated with neoplastin on the basis of the control group.Observation and comparison were made on self-rating anxiety scale (SAS) score,selfrating depression scale (SDS) score and 24 h urine volume after treatment between the two groups.Results After treatment,the experimental group had lower SAS and SDS score respectively as (41.68±5.37) and (16.98±4.37) points than (50.99±6.45) and (23.45±5.97) points in the control group.Their difference was statistically significant (P<0.05).The experimental group had less 24 h urine volume as (1234.98±80.35) ml/24 h than (1567.78±73.81) ml/24 h in the control group,and the difference was statistically significant (P<0.05). Conclusion Xinhuosu can obviously improve 24 h urine volume of elderly patients with heart failure,improve their mental state and quality of life.It is worthy of clinical promotion.
作者
杨飞
YANG Fei(Department of Internal Medicine,Shenyang Songliao Hospital of Traditional Chinese Medicine,Shenyang 110000,China)
出处
《中国现代药物应用》
2019年第13期79-80,共2页
Chinese Journal of Modern Drug Application
关键词
冻干重组人脑利钠肽
老年心力衰竭
尿量
精神状态
Lyophilized recombinant human brain natriuretic peptide
Elderly heart failure
Urine volume
Mental state