新活素维持量连续给药对急性心力衰竭治疗的影响及护理体会

Effect and Nursing Experience and Maintaining Continuous Administration of rhBNP on the Treatment of Acute Heart Failure

目的:探讨新活素维持量连续给药对急性心力衰竭治疗的影响和护理体会。方法:选取2015年3月-2018年10月于笔者所在医院治疗的急性左心衰竭患者67例,按入院顺序随机分为观察组和对照组。对照组给予新活素常规给药方法,观察组采用维持量连续给药方式。观察两组临床疗效,比较两组的生活质量及不良反应差别。结果:观察组总有效率为79.41%(27/34),高于对照组的66.67%(22/33),差异无统计学意义(χ^2=1.798;P=0.407)。观察组体力限制、社会关系、心里情绪、疾病症状评分和总分均低于对照组,心理情绪评分和总分比较,差异有统计学意义(P<0.05)。观察组不良反应发生率为8.82%(3/34),少于对照组的33.33%(11/33),差异有统计学意义(χ^2=4.495,P=0.034)。结论:新活素维持量连续给药方式与常规给药方式疗效相当,但维持量连续给药方式的不良反应发生率低,更利于临床护理。

Objective:To investigate the effect and nursing experience of maintaining continuous administration of rhBNP on the treatment of acute heart failure.Method:A total of 67 patients with acute left heart failure who were treated in our hospital from March 2015 to October 2018 were randomly divided into the observation group and the control group according to the order of admission.The control group was given the conventional administration of rhBNP,and the observation group was given the maintaining continuous administration.The clinical efficacy of the two groups of patients was observed,and the quality of life and adverse reactions were compared between the two groups.Result:The total effective rate of the observation group was 79.41%(27/34),which was higher than that of the control group(66.67%)(22/33),but the difference was not statistically significant (χ^2=1.798,P=0.407).The physical strength limit,social relationship,mental emotion,symptom scores and total score in the observation group were lower than those of the control group,but only the mental emotion scores and total scores comparison,the difference was statistically significant(P<0.05).The incidence of adverse reactions was 8.82%(3/34) in the observation group,less than 33.33%(11/33) of the control group,and the difference was statistically significant (χ^2=4.495,P=0.034).Conclusion:The effect of maintaining continuous administration of rhBNP is equivalent to that of conventional administration,but the maintaining continuous administration has a low incidence of adverse reactions,which is more conducive to clinical nursing.