摘要
目的研究黑沙蒿不同溶剂提取物的化学成分。方法采用色谱法对黑沙蒿不同溶剂提物进行分离,经核磁共振数据分析确定化合物结构式。结果从黑沙蒿不同提取物中分离得到13个化合物,分别为spathulenol (1)、乌苏醇(2)、6,7,8-三甲氧基香豆素(3)、对羟基苯乙酮(4)、3-甲氧基-4-羟基苯乙酮(5)、对羟基苯甲醛(6)、3-甲氧基-4-羟基苯甲醛(7)、3,4-二羟基苯甲醛(8)、2-[hexadiin-(2.4)-yl]-phenol (9)、dehydrofalcarinol (10)、heptadeca-1,9(Z)-16-trien-4,6-diyn-3,8-diol (11)、二氢松柏醇(12)和松柏醇(13)。结论化合物1~13均为首次该植物中分离得到。
OBJECTIVE To study the chemical constituents of different solvent extracts from Artemisia ordosica. METHODS The chemical constituents of different solvent extracts from A. ordosica were isolated by chromatography. Their structures were identified by NMR data analysis. RESULTS Thirteen compounds, namely spathulenol(1), uvaol(2), 6,7,8-trimethoxycoumarin(3), 4-hydroxylacetophenone(4), 3-methoxy-4-hydroxyacetophenone(5), 4-hydroxybenzaldehyde(6), 4-hydroxy-5-methoxybenzaldehyde(7), 4,5-dihydroxybenzaldehyde (8), 2-[hexadiin-(2.4)-yl]-phenol(9), dehydrofalcarinol(10), heptadeca-1,9(Z)-16-trien-4, 6-diyn-3,8-diol(11), dihydroconiferyl alcohol(12), and coniferyl alcohol(13) were obtained from the different solvent extracts from A. ordosica. CONCLUSION Compounds 1-13 are isolated from this plant for the first time.
作者
郝俊生
王青虎
巴森吉日嘎拉
宫菊花
包文强
毕力格图
HAO Jun-sheng;WANG Qing-hu;BA-SHENG-JI-RI-GA-LA;GONG Ju-hua;BAO Wen-qiang;BILIGETU(College of Traditional Mongolian Medicine,Inner Mongolia University for Nationalities,Tongliao 028000,China;Inner Mongolia Medical Engineering Technology Research Institute,Tongliao 028000,China)
出处
《中国药学杂志》
CAS
CSCD
北大核心
2019年第11期863-866,共4页
Chinese Pharmaceutical Journal
基金
蒙医药标准化国家合作科技创新项目子课题资助(MDKBZH2018017)
国家级重点实验室平台能力建设项目资助(NMKJZX1702)
内蒙古民族大学研究生创新项目资助(NMDSS1836)
内蒙古自治区人民政府蒙医药标准化项目资助(MB017)
关键词
黑沙蒿
化学成分
分离
鉴定
乌苏醇
松柏醇
Artemisia ordosica
chemical constituent
isolation
identification
uvaol
coniferyl alcohol
