甲状腺乳头状癌超声特征与颈侧区淋巴结大量转移的相关性

Correlation between sonographic features of papillary thyroid carcinoma and high volume lateral neck lymph node metastasis

目的探讨甲状腺乳头状癌(papillary thyroid carcinoma, PTC)超声特征术前对颈侧区淋巴结大量转移的预测价值。方法收集甲状腺全切及颈侧区淋巴结清扫术,术后病理证实为颈侧区淋巴结转移的PTC患者83例,分析PTC超声特征与颈侧区淋巴结大量转移之间的关系。结果83例患者中发生颈侧区淋巴结大量转移者18例,无颈侧区淋巴结大量转移者65例。两组患者在性别方面相匹配,无显著差异;在结节的位置、边界、形态、纵横比、微钙化、被膜侵犯等方面差异亦无统计学意义( P >0.05);与无颈侧区淋巴结大量转移者相比,年龄≤45岁、病灶多发、原发病灶直径较大者易发生颈侧区淋巴结大量转移,两组之间差异有统计学意义( P <0.05)。结论甲状腺乳头状癌超声征象对颈侧区淋巴结大量转移风险的评估有一定的参考价值。

Objective To investigate the correlation between sonographic features of papillary thyroid carcinoma (PTC) and high volume lateral neck lymph node metastasis. Methods From January 2017 to NovembeR2018, 83 patients with pathologically confirmed PTC and lateral neck lymph node metastasis were retrospectively reviewed. All patients had undergone total thyroidectomy with lateral lymph node dissection. The aim was to study the relationship between sonographic features and high volume lateral lymph node metastasis. Results There were 18 cases with high volume lateral neck lymph nodes metastasis and 65 cases without high volume lateral neck lymph nodes metastasis. There were no significant differences among features of the sex, location, boundary, shape, longitudinal/transveral ratio, microcalcification, capsulaRinvasions. Compared with PTC without high volume lateral lymph node metastasis, PTC with high volume metastasis more frequently had largeRtumoRsize, multifocal, age ≤ 45 years ( P <0.05). Conclusion Sonographic features of papillary thyroid carcinoma has correlation with high volume lateral neck lymph node metastasis.