慢性阻塞性肺疾病急性加重预警研究进展

Advances in prediction of acute exacerbation of chronic obstructive pulmonary disease

慢性阻塞性肺疾病(COPD)是我国乃至全世界的常见病之一,是目前世界上第4大死亡原因之一,其最主要原因是慢性阻塞性肺疾病急性加重(AECOPD)反复发作,导致住院率增加,造成严重的社会问题和经济负担。但是,目前AECOPD的诊断主要依据临床症状,尚缺乏有效应用于临床的客观指标。本文主要对AECOPD的定义、危险因素及预警研究进展作一综述。

Chronic obstructive pulmonary disease (COPD) is one of the most common diseases in China and the world.It is one of the fourth leading causes of death in the world.The main cause is the acute exacerbation of chronic obstructive pulmonary disease ( AECOPD),which can increase in the rate of hospitalization and can result in serious social and economic burden. However, at present,the diagnosis of COPD acute exacerbation is based on clinical symptoms,and there is still a lack of effective clinical marker.This paper mainly describes the definition,risk factors and predict research progress of AECOPD.