精神疾病预测量表在抑郁症临床诊断的应用价值

Applicative Value of Mental Disorder Predictive Scale in clinical disgnosis of depressive disorder

目的探讨精神疾病预测量表(MDPS)在抑郁症筛查中的应用价值。方法根据美国精神障碍诊断与统计手册第4版(DSM-IV-TR),选取186例抑郁症患者(抑郁症组)、118例其他精神障碍患者(其他精神障碍组)及302例正常对照者(正常对照组)进行MDPS评估,分析三者间差异;以MDPS的11个因子为自变量,临床诊断为因变量,进行Logistic多元回归,分析回归模型预测成功率。结果抑郁症组、其他精神障碍组的MDPS总分及各因子分均显著高于正常对照组(P<0.01);抑郁症组在个性内向、心理防御不良、社会支持缺乏、抑郁显著高于其他精神障碍组患者(P<0.01);Logistic回归显示,应激源、精神病性、抑郁和神经症四个因子对抑郁症的诊断有显著的预测作用(χ^2=473.509,P=0.000),模型预测成功率达90.6%。结论MDPS评估与抑郁症临床诊断具有较高的一致性,可作为抑郁症筛查的有效指标。

Objective To explore the assessment value of the Mental Disorder Predictive Scale(MDPS)for the screening of depressive disorder.Methods According to the diagnostic criteria of DSM-IV-TR,we investigated 186 depressive disorder patients,118 non-depressive disorder patients and 302 normal controls assessed with MDPS and analyzed the differences between the three group.We used 11 factor scores as the independent variables and clinical diagnosis as the dependent variables,Logistic multiple regression model and used the regression model to predict the success rate.Results The total score and all factor scores of depressive disorder group and other mental disorder group were significantly higher than those of the control group(P<0.01);Factor scores of individual introversion,mental defense maladjustment,social support lack,depression in depressive disorder group were significantly higher than other mental disorder group(P<0.01).Factors of stressor,psychosis,depression and neurosis have significant predictive effect on the diagnosis of depression(χ^2=473.509,P=0.000)and predictive effects of logistic regression model was 90.6%. Conclusion MDPS assessment has highly accordance to diagnosis of depressive disorder and could serve as a value instrument for screening of depressive disorder.