二氧化硅@裸银纳米颗粒微球制备及其对大肠杆菌活性的影响

Preparation of Silica@Bare Silver Nanoparticle Microspheres and Their Effects on Activity of Escherichia coli

以SiO2微球为载体,利用其表面可自动吸附与还原银离子的能力,制备新型二氧化硅@银纳米颗粒微球复合材料(SiO2@AgNPs),并用透射电镜、Raman光谱、X射线光电子能谱等对其进行表征,测试其对大肠杆菌的抑菌性能.结果表明:当SiO2@AgNPs质量浓度为2.0mg/mL时,复合材料的抑菌率为99.8%;当银纳米颗粒表面含有稳定剂聚乙烯吡咯烷酮时,其抑菌率降低.表明稳定剂可保护银纳米颗粒的单分散性,但不利于其抑菌性的发挥。

The silica microspheres were used as carriers to absorb and reduce silver ions automatically on the surface of microspheres,and a new type of composite material of silica@silver nanoparticle microspheres (SiO 2@Ag NPs) was obtained. The silver nanoparticles were characterized by trans mission electron microscopy (TEM),Raman spectroscopy and X-ray photoelectron s pectroscopy (XPS),and the bacteriostasis of Escherichia coli was tested. The results show that the antibacterial rate of the composite is 99.8% when the mass concentration of SiO 2@Ag NPs is 2.0 mg/mL,and the an tibacterial rate decreases when the surface of silver nanoparticles contains stabilizer (polyvinyl pyrrolidone). Therefore, the stabilizer can protect the monodispersity of silver nanoparticles,but it is not conducive to its bacteriostatic effect.