在生化检验对肝硬化诊断的临床意义

Clinical Significance of Biochemical Examination in the Diagnosis of Liver Cirrhosis

目的观察在肝硬化患者的临床诊断当中,生化检验的具体应用效果。方法选择该院在2017年4月-2018年3月期间收治的47例肝硬化患者为研究组,再选择同一时间段内在该院进行健康体检的47名健康人作为参照组,两组研究对象都需要接受生化检验,对两组对象的生化指标以及血清酶值进行观察。结果研究组对象的总胆红素(52.1±2.4)μnol/L,高于参照组(3.9±1.3)μnol/L,(t=121.065,P=0.000<0.05);研究组天冬氨酸氨基转移酶(61.2±6.7)U/L,高于参照组(10.7±4.1)U/L,(t=44.076,P=0.000<0.05);研究组白蛋白(26.6±2.7)g/L,低于参照组(41.2±4.5)g/L,(t=19.073,P=0.000<0.05);研究组白蛋白/球蛋白比值为(0.8±0.3),低于参照组(1.9±0.8),(t=8.826,P=0.000<0.05)。结论针对肝硬化患者的临床诊断而言,给予其生化检验的实际效果较好,该方案值得在临床中推广。

Objective To observe the specific application effect of biochemical test in the clinical diagnosis of liver cirrhosis. Methods A total of 47 patients with liver cirrhosis admitted to our hospital from April 2017 to March 2018 were selected as the study group. And 47 healthy people who underwent physical examination in our hospital during the same period were selected as the reference group. Both groups of subjects need to undergo biochemical tests, and the biochemical indexes and serum enzymes of the two groups were observed. Results The total bilirubin (52.1±2.4)μnol/L of the study group was higher than the reference group (3.9±1.3)μnol/L,(t=121.065, P=0.000<0.05). Aspartate aminotransferase in the study group (61.2±6.7) U/L was higher than that in the reference group (10.7±4.1) U/L,(t=44.076, P=0.000<0.05). Albumin in the study group (26.6±2.7) g/L was lower than that in the reference group (41.2±4.5) g/L,(t=19.073, P=0.000<0.05). The albumin/globulin ratio of the study group was (0.8±0.3), which was lower than that of the reference group (1.9±0.8),(t=8.826, P=0.000<0.05). Conclusion For the clinical diagnosis of patients with liver cirrhosis, the actual effect of biochemical test is better, which is worth popularizing in clinical practice.