卡络磺钠联合奥美拉唑治疗上消化道出血的临床效果及平均止血时间分析

The Clinical Effect and Mean Time of Hemostasis in the Treatment of Upper Gastrointestinal Bleeding with the Combination of Sodium Carbazoate and Omeiramine

目的观察上消化道出血患者接受卡络磺钠联合奥美拉唑治疗的效果,并观察患者止血时间。方法选取该院2017年1月-2018年12月期间收治的52例上消化道出血患者为观察对象,按照患者治疗方案分为两组,对照组(26例)采用奥美拉唑治疗,观察组(26例)采取卡络磺钠联合奥美拉唑治疗,对比两组患者治疗的效果。结果对照组患者治疗总有效率为88.4%,平均止血时间为(34.9±2.1)h,血红蛋白指数为(97.3±21.5)g/L;观察组患者治疗总有效率为96.1%,平均止血时间为(25.0±1.8)h,血红蛋白指数为(110.0±28.6)g/L,两组结果对比差异有统计学意义(χ^2=13.034,t=15.074,t=15.972,P<0.05),两组患者不良反应率分别为26.9%、23.0%,差异无统计学意义(χ^2=0.116,P>0.05)。结论上消化道出血患者以卡络磺钠联合奥美拉唑治疗,可有效提升治疗效率,尽早止血,且治疗不良反应率低,值得在临床治疗中推广应用。

Objective To observe the effect of the treatment of the patients with upper gastrointestinal bleeding with the combination of carbazoon and omeiramine, and to observe the time for hemostasis of the patients. Methods A total of 52 patients with upper gastrointestinal bleeding from January 2017 to december 2018 were divided into two groups according to the treatment plan of the patient. The control group (26 cases) was treated with omeprazole, while the observation group (26 cases) was treated with carbazoon combined with omeprazole, and the effects of treatment in the two groups were compared. The effect of treatment on the two groups was compared. Results The total effective rate of treatment in the control group was 88.4%, the mean hemostasis time was (34.9±2.1) h, the hemoglobin index (97.3±21.5) g/L. The total effective rate of the observation group was 96.1%, the mean hemostasis time was (25.0±1.8) h, and the hemoglobin index (110.0±28.6) g/L, The difference between the two groups was statistically significant (χ^2=13.034, t=15.074, t=15.972,P<0.05). The adverse reaction rates of the two groups were 26.9% and 23.0%, respectively (χ^2=0.116,P>0.05). Conclusion Carosulfonate sodium combined with omeprazole can effectively improve the therapeutic efficiency in the treatment of upper gastrointestinal bleeding patients. It can stop bleeding as soon as possible, and the rate of adverse reactions is low. Therefore, it is worth popularizing and applying in clinical treatment.