卡前列素氨丁三醇注射液联合宫腔填纱对前置胎盘剖宫产患者产后出血量及不良反应的影响

Influence of untoward effect and postpartum hemorrhage for placenta previa cesarean section patients by Caprostatin Triol Injection combined with uterine cavity filling

目的探讨卡前列素氨丁三醇注射液联合宫腔填纱对前置胎盘剖宫产患者产后出血量及不良反应的影响情况。方法选取2016年6月~2018年7月广东省茂名市电白区妇幼保健院收治的120例前置胎盘剖宫产患者作为研究对象,依据治疗方式的不同将其分为对照组和观察组,每组各60例。对照组患者使用宫腔填纱,观察组患者在对照组治疗基础上联合卡前列素氨丁三醇注射液进行治疗。观察两组患者的前置胎盘剖宫产患者第三产程时间、产后2、24h出血量、临床疗效、不良反应总发生率情况。结果观察组患者的第三产程时间短于对照组,产后2、24h出血量均少于对照组,观察组患者的临床治疗总有效率高于对照组,观察组患者的恶心、面色潮红、腹泻、血压升高等不良反应总发生率低于对照组,差异均有统计学意义(P<0.05)。结论卡前列素氨丁三醇注射液联合宫腔填纱治疗前置胎盘剖宫产患者,明显降低产后出血和不良反应发生率,提高临床效果,值得临床推广应用。

Objective To approach untoward effect and postpartum hemorrhage for placenta previa cesarean section patients by Caprostatin Triol Injection combined with uterine filling. Methods A total of 120 cases clinical data of placenta previa cesarean section patients in Maternal and Child Health Care Hospital of Dianbai District in Maoming City from June 2016 to July 2018 were selected as the study objects. They were divided into the control group and the observation group according to the different treatment methods, each group had 60 cases. Patients in the control group used uterine cavity filling, while in the observation group were treated with Caprostatin Triol Injection on the basis of the control group. The third labor time, postpartum hemorrhage after 2 h and postpartum hemorrhage after 24 h, clinical effect,total untoward effect of two group placenta previa cesarean section patients were detected. Results The third labor time of observation group patients were shorter than control group, postpartum hemorrhage after 2 h and postpartum hemorrhage after 24 h of observation group were less than control group, the clinical treatment total effect rate of observation group patients were higher than control group, the differences were statistically significant (P<0.05). The total untoward effect of observation group patients, such as the nausea, red complexion, diarrhea and the elevated blood pressure were higher than control group, the differences were statistically significant (P<0.05). Conclusion The placenta previa cesarean section patients by Caprostatin Triol Injection combined with uterine cavity filling, which could decrease postpartum hemorrhage and untoward effect, increase clincial result, it is worth to be used.