MRI联合CT影像学在肺癌中的诊断效能

Diagnostic efficacy of MRI combined with CT imaging in lung cancer

目的探讨磁共振成像(MRI)联合计算机断层扫描(CT)影像学检查对肺癌的诊断效能。方法选取疑似肺癌患者88例,均给予MRI常规序列、弥散加权成像扫描和CT检查。观察MRI、CT单独及联合检查诊断肺癌的效能,并对不同临床特征肺癌患者的表观弥散系数(ADC)进行比较。结果88例疑似肺癌患者中,最终确诊肺癌患者51例;MRI联合CT检查诊断肺癌的灵敏度和阴性预测值均高于MRI检查,特异度和阳性预测值均高于CT检查,差异均有统计学意义(P﹤0.05)。小细胞癌患者的ADC值明显低于鳞癌和腺癌患者(P﹤0.01);低分化肺癌患者的ADC值低于高分化和中分化肺癌患者(P﹤0.01)。结论MRI联合CT检查在肺癌中有较高的诊断价值,其中MRI弥散加权成像ADC值与肺癌患者的病理类型和分化程度有关。

Objective To explore the value of magnetic resonance imaging (MRI) combined with computed tomography (CT) scan in the diagnosis of lung cancer. Method A total of 88 cases with suspected lung cancer were examined with routine MRI sequence, diffusion-weighted imaging and CT scan. The efficacy of MRI, CT alone and combined examination in the diagnosis of lung cancer were observed, apparent diffusion coefficient (ADC) values were compared among patients with different clinical characteristics. Result Among the 88 cases with suspected lung cancer, 51 were finally diagnosed as lung cancer;the sensitivity and negative predictive value of MRI combined with CT in the diagnosis of lung cancer were higher than those of MRI, the specificity and positive predictive value of MRI combined with CT in the diagnosis of lung cancer were significantly higher than those of CT scan (P<0.05). The ADC value of small cell carcinoma was significantly lower than that of squamous cell carcinoma and adenocarcinoma (P<0.01);besides, the ADC value of poorly differentiated lung cancer was significantly lower than that of highly and moderately differentiated lesions (P<0.01). Conclusion MRI combined with CT has high diagnostic value in lung cancer, and the ADC value of MRI diffusion- weighted imaging is related to pathological type and degree of differentiation.