29例临床药师参与儿童抗真菌治疗的会诊病例分析

Analysis of the Clinical Pharmacists Participating in the Consultation for 29 Antifungal Therapeutic Cases in Paediatrics

目的总结临床药师参与儿童真菌病例会诊的经验,探讨临床药师在儿童抗真菌治疗中的工作切入点。方法通过分析29例药师会诊儿童真菌感染病例,对患者性别、年龄、会诊科室,基础疾病,可疑感染部位,真菌病原学检查结果、会诊意见及采纳情况、治疗效果等进行统计分析。结果 29例患儿中1岁以内的婴幼儿为15例占51.72%;主要会诊科室为外科占总病例数的48.28%。29例病例中真菌培养阳性的共25例,其中霉菌4株(16.00%),念珠菌21株(84.00%)。会诊意见被临床采纳的28例,未被采纳的1例。21例采纳临床药师建议且进行抗真菌治疗的患者中,16例有效,占76.19%。结论临床药师参与儿童真菌治疗,能帮助临床医生制订更佳的真菌治疗方案,为患儿提供更好的用药安全保障。

OBJECTIVE To summarize the experience of antifungal therapeutic consultations in pediatric patients, which clinical pharmacists participating in and to explore the points that clinical pharmacists can involve into the pediatric antifungal therapeutic work. METHODS The medical records of the 29 cases with antifungal therapeutic consultations of clinical pharmacists were analyzed, and the data including gender, age, consultation departments, primary diseases, suspicious infection sites, fungus culture results, disposal opinions, suggestion adoption and treatment outcome were statistically analyzed. RESULTS Among the 29 cases, there were 15 infants (51.72%) younger than 1 year old. The main consultation department was surgical department which account for 48.28% cases. 25 cases had positive fungal culture results, in which 4 cases ( 16.00%) were molds and 21 cases ( 84.00%) were Candida. The suggestions of clinical pharmacists were adopted in 28 cases, except for one case. The 21 cases used antifungal drugs suggested by clinical pharmacies, 16 cases (76.19%) of them were supposed to be effective. CONCLUSION Clinical pharmacies participating in the antifungal therapy of pediatric patients may help clinicians developing better fungal treatment options and providing better drug safety guarantee for children.