复方甘草酸苷联合卡泊三醇治疗银屑病疗效

Therapeutic Effect of Compound Glycyrrhizin Combined With Calcipotriol on Psoriasis Vulgaris

目的研究复方甘草酸苷治疗寻常型银屑病的临床疗效。方法选择我院2016 年1 月—2018 年5 月于我院接受治疗的寻常型银屑病门诊患者90 例,根据治疗方式差异分为对照组(n =44)与观察组(n =46)。对照组卡泊三醇治疗,观察组则予以复方甘草酸苷联合卡泊三醇治疗。比较两组疗效、皮损面积严重程度变化以及不良反应。结果观察组(95.65%)临床总有疗效高于对照组临床总有疗效(79.55%)(P< 0.05)。治疗前,两组皮损面积严重程度评分比较差异无统计学意义(P > 0.05),经治疗后,观察组皮损面积严重程度评分低于对照组(P< 0.05)。两组无严重不良反应发生。结论复方甘草酸苷联合卡泊三醇治疗寻常型银屑病疗效突出,有助于减小皮损面积及程度,促使患者早日康复。

Objective To study the clinical efficacy of compound glycyrrhizin in the treatment of psoriasis vulgaris. Methods A total of 90 patients with psoriasis vulgaris who were treated in our hospital from January2016 to May 2018, in our hospital were divided into control group (n =44) and observation group (n =46). The control group was treated with calcipotriol, and the observation group was treated with compound glycyrrhizin combined with calcipotriol. The efficacy of the two groups, the severity of the lesion area and the adverse reactions were compared. Results The total clinical efficacy of the observation group (95.65%) was higher than that of the control group (79.55%)(P < 0.05). Before treatment, there was no significant difference in the severity of lesions between the two groups (P > 0.05). After treatment, the severity of lesions in the observation group was lower than that in the control group (P < 0.05). No serious adverse reactions occurred in the 2 groups. Conclusion Compound glycyrrhizin combined with calcipotriol is effective in the treatment of psoriasis vulgaris, which helps to reduce the area and extent of skin lesions and promote the early recovery of patients.