期刊文献+

银屑病治疗药物的专利分析

Patent Analysis of Psoriasis Drugs
下载PDF
导出
摘要 银屑病是长期性的慢性炎症性皮肤病,患者基数多,市场大,属于国内外科研人员研究的重要方向。本文利用专利信息以及药物注册信息对银屑病药物的发展状况进行了分析。结果表明,银屑病治疗药物开始逐步从化学药向生物药进行过渡,抗体类药物是目前研发的热点方向,特别是TNF靶点以及IL靶点更是热门中的焦点。本文还对制药企业提出了相应的发展建议。 Psoriasis is a chronic infl ammatory dermatosis with a large number of patients and a large market. It is an important research fi eld for domestic and foreign researchers. In this paper, the development of psoriasis drugs is analyzed by using patent information and drug registration information. The results shows that psoriasis drugs begin to change gradually from chemical drugs to biological drugs. The research of antibody drugs is a key focus area, especially TNF and IL targets. This paper also puts forward some suggestions for the development of pharmaceutical enterprises.
作者 靳春鹏 代月函 JIN Chunpeng;DAI Yuehan(Patent Examination Cooperation (Beijing) Center of the Patent Office, CNIPA, Beijing 100160)
出处 《中国发明与专利》 2019年第7期122-128,共7页 China Invention & Patent
关键词 银屑病 化学药 抗体 专利分析 psoriasis chemical drugs antibody patent analysis
  • 相关文献

参考文献1

二级参考文献33

  • 1Rachakonda TD, Schupp CW, Armstrong AW. Psoriasis prevalence among adults in the United States[J]. J Am Acad Dermatol,2014,70 (3) : 512-516.
  • 2Lowes MA, Bowcock AM, Krueger JG. Pathogenesis and therapy of psoriasis[J]. Nature,2007, 445(7130) : 866-873.
  • 3Beige K, Bruck J, Ghoreschi K. Advances in treating psoriasis [J]. F1000prime reports,2014,6:4.
  • 4Farber EM, Abel EA, Cox AJ. Long-term risks of psoralen and UV-A therapy for psoriasis[J]. Archives of dermatology, 1983,119(5) :426-431.
  • 5Gniadecki R, Kragballe K, Dam TN, et al. Comparison of drug survival rates for adalimumab, etanercept and infliximab in patients with psoriasis vulgaris [J ]. British J dermatol, 2011,164(5) : 1091-1096.
  • 6Chamian F, Lin SL, Lee E, etal. Alefacept (anti-CD2) cau- ses a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tom) in psoriasis[J]. J Transl Med,2007,5 : 27.
  • 7Papoutsaki M, Costanzo A. Chimenti S. Emerging treatments in the management of psoriasis biological targeting with ustekinumab[J]. Clin Cosmet Investig Dermatol, 2009, 2 : 95- 103.
  • 8Micali G, Lacarrubba F, Musumeci ML, et al. Cutaneous vascular patterns in psoriasis[J]. Int J Dermatol,2010,49(3) : 249-256.
  • 9Biswas S, Myszor M, De Silva A. Management of psoriasis in patients treated with anti-TNF--alpha therapy for inflammato- ry bowel disease[J]. J Crohns Colitis, 2013,7(12) : 708-709.
  • 10Calabrese LH. Molecular differences in anticytokine therapies [J]. C[in Exp Rheumatol, 2003,21 (2) :241-248.

共引文献35

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部