延迟断脐带对妊娠期糖尿病孕妇分娩新生儿血糖的影响

Effect of delayed umbilical cord clamping on blood glucose of full-term neonates born to mothers with gestational diabetes mellitus

目的探讨延迟断脐带对妊娠期糖尿病孕妇分娩的足月新生儿血糖的影响。方法本研究纳入120例自然分娩的妊娠期糖尿病产妇,均为单胎妊娠,随机分为观察组与对照组,各60例。对照组新生儿在娩出后立即断脐,观察组新生儿在娩出后2min断脐(若2min之内脐带终止搏动,立即断脐)。观察2组新生儿脐静脉血血糖值和娩出后2h足跟血血糖值,记录2组娩出后2h内血糖变化,比较2组新生儿血糖干预情况。结果对照组新生儿娩出后2h足跟血血糖水平低于观察组新生儿,血糖波动水平较观察组明显,差异有统计学意义(P<0.01)。结论延迟断脐对预防妊娠期糖尿病孕妇自然分娩的足月新生儿出生后低血糖有积极作用。

Objective To investigate the effect of delayed umbilical cord clamping on blood glucose of full-term neonates born to mothers with gestational diabetes mellitus.Methods Totally 120 full-term pregnant women with gestational diabetes mellitus and spontaneous labor of were included and assigned into the control group(n=30)and the observation group(n=30).In the control group,the umbilical cord was clamped immediately after delivery.In the observation group,the umbilical cord was clamped 2 minutes after delivery,the umbilical cord was clamped immediately if the umbilical pulse-wave ceased with 2 minutes after delivery).The blood?glucose in umbilical vein and heel-prick blood glucose 2 hours after delivery were evaluated and compared between two groups.Results The heel-prick blood glucose of neonates in the control group was lower than that of neonates in the observation group,indicating a more obvious blood glucose fluctuation after delivery(P<0.01).Conclusion The delayed umbilical cord clamping is potentially effective to control postnatal hypoglycemia in full-term neonates born to mothers with gestational diabetes mellitus.