摘要
目的分析宁夏某医院中药不良反应发生情况,探讨使用中药发生不良反应的特点。方法收集某院2011-2017年154例中药不良反应报告。按患者性别、年龄、给药途径、处方类别、种类、涉及系统及临床症状、不良反应的级别及转归情况进行分析。结果中药不良反应中主要以中药注射剂为主(79.87%),活血化瘀类引起的不良反应最多,其次为清热解毒类,ADR报告中前5位为中药注射剂,最多的药品是注射用血栓通、喜炎平及痰热清注射液,以皮肤损害为最常见不良反应。结论临床应加强中药的不良反应报告和监测工作,以确保临床合理用药。
Objective To investigate the adverse drug reaction(ADR)of traditional Chinese medicine in a Hospital of Ningxia province,to analyze the characteristics and regularities of the occurrences of ADR.Methods A total of 154 ADR reports in this hospital from 2011 to 2017 were collected retrospectively.The data in respect of gender and age,routes of administration,forms of medicines,drugs species,systems and organs involved in ADR,clinical manifestations,distribution of ADR levels and prognoses were analyzed statistically.Results ADR reports were most likely caused by TCM injections(79.87%).The ratio of ADRs caused by blood-activating and stasis-eliminating was the highest.Heat-clearing and detoxifying took the second place.Injection occupied the majority of top five drugs inducing ADR,among which Xueshuantong,Xiyanping and Tanreqing injections were the leaders as reported.Lesion of skin was the most commonly adverse drug reaction.Conclusion Clinical reports and monitoring of adverse reactions of traditional Chinese medicine should be strengthened to ensure rational use of drugs in clinic.
作者
赵培
李文静
宫凯敏
ZHAO Pei;LI Wenjing;GONG Kaimin(Yinchuan Hospital of Traditional Chinese Medicine,Yinchuan 750001,China)
出处
《宁夏医科大学学报》
2019年第5期513-516,共4页
Journal of Ningxia Medical University
基金
宁夏医科大学面上项目(XM2016123)
关键词
中药
不良反应
合理用药
宁夏
traditional chinese medicine
adverse drug reaction
rational drug use
Ningxia