不同年龄乳腺癌患者超声影像学特征对比分析

Comparative analysis of characteristics of different age of breast cancer patients with ultrasound imaging

目的:探讨不同年龄乳腺癌患者超声影像学特征。方法:将经手术治疗且术后病理证实乳腺癌的195例根据年龄分为三组,其中≤40岁为青年组、>41岁且<60岁为中老年组、≥60岁为老年组,对比三组患者的超声恶性征象、病理结果及免疫组化结果。结果:青年组乳腺癌边缘毛刺征、周边高回声晕环、后方回声衰减、微小钙化灶、异常肿大淋巴结发生率高于中年组及老年组;青年组乳腺癌浸润性非特殊癌Ⅲ级、肿块大小T3+T4、腋下淋巴结转移占比均高于中年组及老年组(P<0.05);青年组的ER阳性、PR阳性发生率均低于中年组及老年组(P<0.05)。结论:青年组的边缘毛刺征、周边高回声晕环、后方回声衰减、微小钙化灶、异常肿大淋巴结超声恶性征象发生率高,且侵袭性强,恶性程度高。

Objective:To explore the ultrasonographic characteristics of breast cancer patients of different ages.Methods: A retrospective study of 195 patients with breast cancer admitted to our hospital was conducted. According to age, patients were divided into three groups: the younger group (≤40 years old), the middle-aged group (41-59 years old), and the older group (≥60 years old). Ultrasound malignant signs, pathological results and immunohistochemical results of the three groups were compared.Results: The incidences of marginal burr sign, peripheral hyperechoic halo ring, posterior echo attenuation, microcalcification and abnormal enlarged lymph nodes in the younger group were higher than those in the middle-aged group and the older group. The proportion of invasive non-special cancer grade Ⅲ, mass size T3+T4 and axillary lymph node metastasis in the younger group was higher than that in the middle-aged group and the older group( P <0.05). The incidence of ER-positive and PR-positive in the younger group was lower than that in the middle-aged group and the older group( P <0.05).Conclusion: In the younger group, the incidence of marginal burr sign, peripheral hyperechoic halo ring, posterior echo attenuation, microcalcification, abnormal enlarged lymph nodes was high, with strong invasiveness and high degree of malignancy.