颅脑创伤镇痛镇静的研究

Study on Analgesia and Sedation of Traumatic Brain Injury

颅脑创伤是临床常见外伤,患者均伴有明显的疼痛、躁动及应激反应,导致心率过速、血压升高、颅内压上升等,增加再出血及误伤等风险,不利于治疗的进行。镇痛镇静可减轻患者疼痛程度及应激反应,并达到保护脑组织、促进治疗顺利进行的作用。本研究就颅脑创伤所导致的病理改变、镇痛和镇静的必要性、常用镇痛和镇静药物及相关争论进行综述,旨在为颅脑创伤的治疗提供参考。

Craniocerebral trauma is a common clinical trauma.Patients are accompanied by obvious pain,agitation and stress reaction,resulting in rapid heart rate,elevated blood pressure,increased intracranial pressure,etc.,increasing the risk of rebleeding and accidental injury,which is not conducive to treatment.Analgesia and sedation can alleviate the pain level and stress response of patients,and achieve the role of protecting brain tissue and promoting the smooth progress of treatment.This study reviews the pathological changes caused by traumatic brain injury,the need for analgesia and sedation,common analgesic and sedative drugs,and related debates,aiming to provide a reference for the treatment of craniocerebral trauma.