磷酸肌酸钠治疗小儿病毒性心肌炎临床效果分析

Clinical Analysis of Sodium Creatine Phosphate in the Treatment of Viral Myocarditis in Children

目的将病毒性心肌炎患儿通过常规治疗基础上加用磷酸肌酸钠治疗与只用常规方法治疗所获得的治疗效果进行比较,对前者的治疗优势进行阐述,评价其治疗效果。方法该次研究,从重庆市潼南区中医院、潼南区妇幼保健计划生育服务中心在2015年3月—2018年3月,3年时间内收治的病毒性心肌炎患者中随机抽取出100例患者,进行试验研究,将其当成该次研究的研究对象,将所有患者按照随机化方法分成两组,每组由50例患者组成,一组患者通过常规方法以及磷酸肌酸钠进行联合治疗,叫做观察组,一组患者单纯的通过常规方法进行医治,叫做对照组。对两组患儿的治疗总有效率、心肌酶水平的恢复时间以及早搏的发生概率进行比较,对两组患儿的治疗效果进行评价,从而为临床提供有力的治疗依据。结果观察组患儿的治疗总有效率为96.00%(48/50),其中治疗后表现为显效的患者有29例,表现为产生一定效果的患者有19例,没有产生效果或者病情加重的患者有2例,对照组患儿的治疗总有效率为80.00%(40/50),其中经治疗后,表现为治疗显著的患者有16例,表现为治疗产生一定效果的患者有24例,没有产生治疗效果或者病情加重的患者有10例,组间差异有统计学意义(χ^2=16.55,P<0.05),观察组患儿的心肌酶水平的恢复时间(8.10±1.30)d,早搏的发生概率为8.00%(4/50),对照组患儿的心肌酶水平的恢复时间:(10.60±1.90)d,早搏的发生概率为20.00%(10/50),两组间差异有统计学意义(t=5.33,χ^2=16.25,P<0.05)。结论病毒性心肌炎患儿在常规治疗基础上联合磷酸肌酸钠治疗,有效的提高治疗效果,显著改善患儿的临床情况,值得在临床中推广应用。

Objective To compare the therapeutic effects of the former treatment of children with viral myocarditis and the treatment of sodium creatine phosphate alone, and to evaluate the therapeutic effect of the former. Methods In this study, the author randomly selected the patients with viral myocarditis who were admitted to Chongqing Weinan District Chinese Medicine Hospital and Weinan District Maternal and Child Health Family Planning Service Center from March 2015 to March 2018. A total of 100 patients were enrolled in the study. They were divided into two groups according to randomization method. Each group was consisted of 50 patients. The observation group was treated by conventional methods and sodium creatine phosphate, while the control group was treated by conventional methods. The total effective rate of treatment, the recovery time of myocardial enzyme level and the probability of premature beats were compared between the two groups, and the therapeutic effects of the two groups were evaluated to provide a strong therapeutic basis for the clinic. Results The total effective rate of treatment in the observation group was 96.00%(48/50), of which 29 cases were markedly effective after treatment, and 19 cases showed a certain effect, no effect or worse. The total effective rate of treatment in the control group was 80.00%(40/50), of which 16 patients showed significant treatment after treatment, 24 patients showed a certain effect on treatment, and 10 patients did not produce therapeutic effect or worsening conditions. The difference between the two groups was statistically significant(χ^2=16.55,P<0.05). The recovery time of myocardial enzyme level and the probability of premature beats were (8.10±1.30) d and 8.00%(4/50) in the observation group, and (10.60±1.90) d and 20.00%(10/50) in the control group. There was a statistically significant difference between the two groups(t=5.33,χ^2=16.25,P<0.05). Conclusion Children with viral myocarditis can be treated with sodium creatine phosphate on the basis of conventional treatment, which can effectively improve the therapeutic effect and significantly improve the clinical situation of children. It is worthy of popularization and application in clinic.