摘要
目的探讨血清Hcy与C反应蛋白检测在心血管类疾病中的诊治及预后应用价值。方法选择2017年7月至11月在浏阳市中医医院接受诊治的心血管类疾病患者163例实施研究,其中,冠心病组:52例;心肌梗死组:51例;心绞痛组:60例。60例健康志愿者作为对照组。对比各组血清Hcy及CRP水平,分析对心血管类疾病的诊断价值。结果冠心病组、心肌梗死组,以及心绞痛组患者的血清Hcy及CRP水平均分别显著高于对照组及H型高血压组(P<0.05)。但冠心病组、心肌梗死组以及心绞痛组患者组间比较血清Hcy及CRP水平差异不显著(P>0.05)。联合血清Hcy及CRP对冠心病、心肌梗死以及心绞痛疾病的诊断准确率显著提高,对心血管类疾病并发症及预后的预测时间显著少于单用血清Hcy或CRP。结论联合检测血清Hcy及CRP,对心血管类疾病患者具有较好的预测价值,效果明显,值得在临床上广泛应用。
Objective To explore the clinical significances of combined detection of serum homocysteine (Hcy) and C- reactive protein (CRP) in cardiovascular diseases.Methods A total of 163 cardiovascular diseases patients,who admitted to Liuyang Municipal Hospital of Traditional Chinese Medicine from Jul.to Nov.2017,were selected as the conronary heart disease group( n =52),the myocardial infarction group( n =51),and angina pectoris group( n =60),and 60 healthy individuals who took health examination were enrolled as the control group.The serum Hcy and CRP were measured.Results The serum Hcy and hs-CRP in the conronary heart disease group,the myocardial infarction group and the angina pectoris group were significantly higher than in the control group ( P <0.05).However,there were no significant difference in detection rate of Hcy and CRP between the conronary heart disease group,the myocardial infarction group and the angina pectoris group( P >0.05).Combined serum Hcy and CRP in the conronary heart disease group,the myocardial infarction group and the angina pectoris group were highest,reaching 96.15%,94.12% and 95.00%,respertively.The prognosis time of combined with Hcy and CRP test for cardiovascular disease complications and prognosis was significantly shorter than that of Hcy and CRP( P <0.05).Conclusion Combined detection of serum Hcy and CRP has predictive value for patients with cardiovascular disease.The effect is obvious,and it is worthy of wide application in clinic.
作者
张硕
孔华珍
何清锋
刘洋
邹江玲
ZHANG Shuo;ZOU Jiangling(Clinical Laboratory of Liuyang Municipal Hospital of Traditional Chinese Medicine,Liuyang,Hunan,410000)
出处
《国际检验医学杂志》
CAS
2019年第A01期124-126,共3页
International Journal of Laboratory Medicine
关键词
心血管类疾病
血清HCY
CRP
诊治
Hcy
C reactive protein
cardiovascular disease
diagnosis and teeatment