多普勒超声成像在乳腺癌及其病理分级诊断中的价值

Value of Doppler Ultrasonography in Diagnosis of Breast Cancer and Its Pathological Grading

目的探讨多普勒超声成像在乳腺癌及其病理分级诊断中的价值。方法选择女性乳腺癌患者190例作为研究对象,根据病理分级情况分为浸润性乳腺癌90例(浸润组)与非浸润性乳腺癌100例(非浸润组),记录所有患者的常规超声与多普勒超声成像特征,判断诊断价值。结果浸润组患者病灶组织常规超声特征为形态不规则、边缘毛刺、内部微钙化、后方回声衰减等,与非浸润组对比差异有统计学意义(P <0. 05)。浸润组患者病灶组织的血流最大流速、阻力指数高于非浸润组,差异有统计学意义(P <0. 05)。浸润组的血流分布部位与非浸润组比较,差异显著(P <0. 05)。多普勒超声成像在乳腺癌浸润性病理分级诊断的敏感性与特异性为98. 9%和97. 0%。结论多普勒超声成像在乳腺癌及其病理分级诊断中能很好判断浸润性状况,清晰显示血流状况与分布情况,有很好的诊断敏感性与特异性。

Objective To explore the value of Doppler ultrasonography in the diagnosis of breast cancer and its pathological grading. Methods 190 cases of female breast cancer were divided into 90 cases of invasive breast cancer( invasive group)and 100 cases of non invasive breast cancer( non invasive group) according to the pathological classification,the imaging characteristics of conventional ultrasound and Doppler ultrasound in all patients were recorded to determine the diagnostic values. Results The characteristics of conventional ultrasound in the invasive group were more with irregular shape,margin burr,Internal microcalcification and posterior echo attenuation,and compared with the non invasive group had statistically significantly difference( P < 0. 05). The maximal flow velocity and resistance index of the lesion tissues in the invasive group were higher than those of the non invasive group,and compared the difference were statistically significant( P < 0. 05);The blood flow distribution in the invasive group was significantly different from that in the non-invasive group( P < 0. 05). The sensitivity and specificity of Doppler ultrasound imaging in breast cancer invasive pathological grading were 98. 8% and 97. 0% respectively. Conclusion The Doppler ultrasound imaging in the diagnosis of breast cancer and its pathological classification can be a good judge of the invasive status,it clearly shows the blood flow status and distribution,and has a good diagnostic sensitivity and specificity.