摘要
目的了解昆明市9县区农村地区女性高危型人乳头瘤病毒(HPV)感染现状。方法采集昆明市9个县区27207例农村女性宫颈脱落细胞,用恒温扩增-荧光法对宫颈脱落细胞进行HPV-DNA扩增,并对结果进行分析。结果西山区筛查1808例,阳性137例,阳性率7. 58%;官渡区筛查3027例,阳性231例,阳性率7. 63%;东川区筛查1564例,阳性133例,阳性率8. 50%;晋宁县筛查4046例,阳性236例,阳性率5. 83%;富民县筛查2001例,阳性137例,阳性率6. 84%;宜良县筛查4862例,阳性320例,阳性率6. 58%;禄劝县筛查4641例,阳性468例,阳性率10. 08%;石林县筛查3254例,阳性172例,阳性率5. 29%;寻甸县筛查2004例,阳性133例,阳性率6. 64%。结论昆明农村地区高危型HPV感染率在5. 29%~10. 08%之间,平均感染率为7. 23%。不同县区高危型HPV感染率及高危HPV13种型、16型、18型等三类HPV感染无统计学差异。
Objective To study the status of human papilloma virus( HPV) infection in rural areas in 9 counties of Kunming. Methods 27207 cases of female cervix cells were collected in 9 counties of Kunming,and the HPV-DNA amplification was carried out by using thermostatic amplification and fluorescence method. Results There were 1808 cases in Xishan,137 positive cases,the positive rate was 7. 58%. There were 3027 cases in Guandu,231 positive cases,the positive rate was 7. 63%.There were 1564 cases in Dongchuan,133 positive cases,the positive rate was 8. 50%. In Jinning,there were 4046 cases,236 positive cases,the positive rate was 5. 83%. There were 2001 cases in Fumin,137 positive cases,the positive rate was 6. 84%. In Yiliang,4862 cases were screened,320 cases were positive,the positive rate was 6. 58%. Luquan screening 4641 cases,positive468 cases,the positive rate was 10. 08%,There were 3254 cases in Shilin,and 172 cases were positive,with a positive rate of5. 29%. In Xundian,2004 cases were screened,there were 133 cases with positive,and the positive rate was 6. 64%. Conclusion The incidence of HPV infection in rural areas of Kunming is between 5. 29% and 10. 08%,with an average infection rate of7. 23%. There were no statistically significant differences in HPV infection and HPV 13 other types,16 and 18 types of HPV infection in different counties.
作者
王喆
张倩
黎丽
李丽
张凤
严涵
WANG Zhe;ZHANG Qian;LI Li(Kunming Maternal and Child Care Hospital,Kunming,600031)
出处
《实用癌症杂志》
2019年第7期1110-1112,共3页
The Practical Journal of Cancer
关键词
人乳头瘤病毒
农村地区
恒温扩增-荧光法
Human papilloma virus
Rural area
Thermostatic amplification-fluorescence method