康莱特注射液对宫颈癌患者放疗的增效分析

Synergistic Effect of Kanglaite Injection on Radiotherapy for Patients with Cervical Cancer

目的探讨康莱特注射液对宫颈癌患者放疗的增效作用。方法选取局部晚期的宫颈癌患者150例,按随机数字法分成观察组和对照组,各组75例。对照组给予单纯放疗治疗,观察组在对照组的基础上给予康莱特注射液治疗。采用KPS评分评估其生活质量。观察比较2组临床疗效、生活质量及不良反应情况。结果经3个月治疗后,观察组总有效率为93. 33%,优于对照组的74. 67%,差异有统计学意义(P <0. 05)。治疗后,观察组患者KSP评分较对照组高,差异有统计学意义(P <0. 05)。观察组患者白细胞减少,恶心、呕吐,腹痛、腹泻的发生率均较对照组低(χ^2=11. 84,P <0. 01;χ^2=10. 76,P <0. 01;χ^2=22. 88,P <0. 01)。结论康莱特注射液可提高乳腺癌患者的放疗效果,降低不良反应的发生率,并改善患者的生活质量。

Objective To explore the synergistic effect of Kanglaite Injection on radiotherapy for patients with cervical cancer. Methods 150 cases of cervical cancer diagnosed by pathology were divided into the observation group and the control group according to the random number method,with 75 cases in each group. The control group was treated with radiotherapy and chemotherapy alone,while the observation group was given Kanglaite Injection treatment on the basis of the control group. The KPS score was used to evaluate the quality of life. The clinical efficacy,quality of life and side effects were compared between the 2 groups. Results After 3 months of treatment,the total effective rate of the observation group was 93. 33% better than the control group( 74. 67%),and the difference was statistically significant( P < 0. 05). After the treatment,the KSP score of the observation group was higher than the control group( P < 0. 05);the incidence of leukocyte reduction,nausea,vomiting,abdominal pain and diarrhea in the observation group was more than that of the observation group. Compared with the control group,the difference was statistically significant(χ^2= 11. 84,P < 0. 01;χ^2= 10. 76,P < 0. 01;χ^2= 22. 88,P < 0. 01). Conclusion Kanglaite Injection can improve the radiotherapy effect of breast cancer patients,reduce the side effects and improve the quality of life of patients.