羊水栓塞的糖皮质激素使用问题

Glucocorticoid use in amniotic fluid embolism

通过分析羊水栓塞的病理生理学基础,糖皮质激素的药理作用等,探讨羊水栓塞治疗中糖皮质激素的使用问题,阐述了糖皮质激素适用于羊水栓塞的观点和争议。目前的结论是尚无明确证据支持常规使用激素治疗羊水栓塞,但糖皮质激素的应用也具有一定理论基础,因此,目前使用大剂量糖皮质激素尚存在争议。

This paper discussed the use of glucocorticoids in amniotic fluid embolism treatment by analyzing the pathophysiological basis of amniotic fluid embolism and the pharmacological effects of glucocorticoids,and expounded the viewpoints and controversial issues supporting the application of glucocorticoids in amniotic fluid embolism.The conclusion is that there is no evidence to support the conventional use of glucocorticoids in the treatment of amniotic fluid embolism,although there is theoretical basis.It is controversial to use or not use large doses of glucocorticoids.