胺碘酮治疗老年急性心肌梗死合并室性心律失常患者的可行性分析

Feasibility analysis of amiodarone in the treatment of elderly patients with AMI complicated with ventricular arrhythmia

目的分析胺碘酮治疗老年急性心肌梗死(AMI)合并室性心律失常患者的临床效果观察。方法2017年1月至2018年1月选取我院收治的96例老年AMI合并室性心律失常患者为研究对象,按照随机抽签法将其分为观察组48例、对照组48例。2组均给予常规治疗,在此基础上,观察组给予胺碘酮治疗,对照组给予利多卡因治疗,对比2组患者临床效果及心功能、心电图检查结果变化情况。结果观察组总有效率高于对照组(P<0.05);治疗前,2组患者心功能指标比较差异无统计学意义(P>0.05);治疗后,观察组心功能指标均优于对照组(P<0.05);治疗前,观察组QTc间期、QPR波群时限及PR间期等心电图检查结果比较差异无统计学意义(P>0.05);治疗后,观察组组QTc间期、QPR波群时限及PR间期均大于对照组(P<0.05)。结论胺碘酮治疗老年AMI合并室性心律失常患者的临床价值显著。

Objective To analyze the clinical effect of amiodarone in elderly patients with acute myocardial infarction (AMI) complicated with ventricular arrhythmia. Methods From January 2017 to January 2018, 96 elderly patients with AMI combined with ventricular arrhythmia admitted to our hospital were selected as research subjects. According to random allocation method, 48 cases were divided into observation group and control group, respectively. Routine treatment was given to both groups. On this basis, amiodarone was given to the observation group and lido caine was given to the control group, The clinical effect, cardiac function and ECG examination results of the two groups were compared. Results The total effective rate of the observation group was higher than that of the control group (P<0.05). Before treatment, there was no significant difference in heart function between the two groups (P> 0.05). After treatment, the cardiac function index of the observation group was better than that of the control group.(P<0.05). Before treatment, there were no significant differences in the QTc interval, QPR group time interval and PR interval in the observation group (P>0.05). After treatment, the QTc interval and QPR group of the observation group were observed. The time limit and PR interval were greater than those of the control group (P<0.05). Conclusion The clinical value of amiodarone in the treatment of elderly patients with AMI complicated with ventricular arrhythmia is significant.