穴位敷贴治疗慢性心力衰竭阳气亏虚、血瘀水停证疗效观察

Observation on Therapeutic Effect of Point Application on Chronic Heart Failure with Yang-Qi Deficiency and Blood Stasis and Water Retention Syndrome

目的:观察穴位敷贴治疗慢性心力衰竭(chronic heart failure,CHF)阳气亏虚、血瘀水停证的临床疗效。方法:选取2016年1月1日至2017年12月31日山东省济宁市中医院治疗的CHF患者160例,随机分为治疗组和对照组,每组80例。两组均给予常规西医基础治疗,治疗组另给予穴位贴敷治疗。观察两组患者临床疗效、6 min步行距离、血浆NTpro BNP、明尼苏达心力衰竭生存质量量表(Minnesota living with heart failure questionnaire,MLHFQ)、生活质量SF-36量表变化情况。结果:治疗组有效率为89. 87%,对照组有效率为72. 15%,治疗组有效率高于对照组,有显著统计学意义(P=0. 006 <0. 01);治疗组治疗后血浆NT-pro BNP水平明显低于对照组,具有显著统计学意义(P=0. 000 <0. 01);治疗组治疗后6 min步行距离明显高于对照组,具有统计学意义(P=0. 000 <0. 01);治疗组治疗后MLHFQ评分明显低于对照组,具有统计学意义(P=0. 000 <0. 01);治疗组治疗后SF-36生命质量评分明显高于对照组,具有统计学意义(P=0. 000 <0. 01)。结论:穴位敷贴能改善CHF阳气亏虚、血瘀水停证患者心功能,提高患者生活质量,改善患者预后。

Objective: To observe the clinical curative effect of point Application on chronic heart failure( CHF) with yang-qi deficiency and blood stasis and water retention syndrome. Methods: A total of 60 CHF patients treated by Jining Hospital of TCM Shandong Province from January 1,2016 to December 31,2017 were randomly divided into the treatment group and the control group,with 80 cases in each group. Both groups were given routine basic treatment of Western medicine,while the treatment group was additionally given point application therapy. The clinical efficacy,6-minute walking distance,plasma NT-pro BNP,Minnesota living with Heart Failure Questionnaire( MLHFQ) and changes of SF-36 scale of quality of life were observed. Results: The effective rate of the treatment group was 89. 87%,and that of the control group was 72. 15%. The effective rate of the treatment group was higher than that of the control group,and the difference was statistically significant( P = 0. 006 < 0. 01). After the treatment,the plasma NT-pro BNP level in the treatment group was significantly lower than that in the control group,and the difference was statistically significant( P = 0. 000 < 0. 01). The walking distance in the treatment group was significantly higher than that in the control group and the difference was statistically significant( P = 0. 000 < 0. 01). After the treatment,the MLHFQ score in the treatment group was significantly lower than that in the control group and the difference was statistically significant( P = 0. 000 <0. 01). The SF-36 quality of life score in the treatment group was significantly higher than that in the control group and the difference was statistically significant( P = 0. 000 < 0. 01). Conclusion: Point application can improve the cardiac function of CHF patients with deficiency of yang-qi and stagnation of blood stasis and water retention,enhance the quality of life and prognosis of patients.