Ⅲa期非小细胞肺癌外科治疗策略进展

Surgical strategy of non-small cell lung cancer with Ⅲa staging

非小细胞肺癌(NSCLC)中Ⅲa期患者占有较大比例,由于Ⅲa期NSCLC包含的临床TNM分期较复杂,且部分患者确诊时已有肿瘤侵及邻近重要器官,因此常常失去完整切除肿瘤的机会,故对于Ⅲa期NSCLC的诊疗手段国内外专家众说纷纭,新辅助治疗、手术治疗以及放化疗均在不同条件下发挥着重要作用,特别是外科手术在综合治疗Ⅲa期NSCLC方面占据着举足轻重的地位。

Patients with Ⅲa staging have a large proportion in non-small cell lung cancer (NSCLC). These patients often lost the opportunity to complete excision of the tumor because the tumor have invaded adjacent vital organs when diagnosed. Besides,Ⅲa staging contains a lot of complicated clinical TNM stages, so, the opinions of experts at home and abroad are various about treatment of NSCLC with Ⅲa staging. Neoadjuvant therapy, surgery, radiation therapy and chemotherapy play important roles under different conditions. Especially surgery is occupying a pivotal position in comprehensive therapy of Ⅲa NSCLC.