池州市2014～2018年手足口病重复感染病例特征与影响因素分析

Epidemiological characteristics and influencing factors of hand foot and mouth disease repetitive infection in Chizhou City from 2014 to 2018

目的了解池州市手足口病重复感染的流行病学特征及其影响因素。方法根据"传染病报告信息管理系统"中的池州市2014~2018年期间手足口病病例个案数据,建立重复感染病例定义,筛选出重复感染病例,采用描述性流行病学方法和多因素logistic回归分析重复感染病例的流行病学特征和影响因素。结果共报告手足口病重复感染229人次,重复感染率为2.02%(229/11 334)。重复感染的发病高峰集中在每年的5~6月份,以≥3岁的幼托儿童为主。报告重复感染病例数最多的为贵池区,城市重复感染率明显高于农村(χ2 =10.614,P=0.001)。多因素分析显示,年龄和居住地是重复感染独立的影响因素。结论手足口病存在重复感染,小年龄组,即小于3岁和农村是重复感染的保护因素,应采取针对性地防控措施,减少手足口病重复感染发生的风险。

Objective To understand the epidemiological characteristics and influencing factors of hand foot and mouth disease (HFMD) repetitive infection in Chizhou City.Methods Based on the data of HFMD in Chizhou City from 2014 to 2018, case definitions were established to screen out the cases of repeated infection.The epidemiological characteristics and influencing factors of repeated infection were analyzed by descriptive epidemiological methods and multivariate logistic regression.Results A total of 229 cases of HFMD were reported.The rate of repeated infection was 2.02%(229/11334).The peak incidence of repetitive infection is concentrated in May-June of each year, mainly in kindergartens older than 3 years old.Guichi District had the highest number of reported cases of repetitive infection ,and the rate of repetitive infection in urban areas was significantly higher than that in rural areas (χ^2=10.614 , P = 0.001).Multivariate analysis showed that age group and residence were independent influencing factors of repeated infection.Conclusion Young age group and rural areas are the protective factors of repeated infection, and specific prevention and control measures should be taken.