椎动脉阻断术前后基底动脉瘤的血流动力学数值模拟分析

Hemodynamic Simulation of Basal Aneurysms Before and After Vertebral Artery Occlusion

探讨椎动脉阻断前后基底动脉瘤的血流动力学变化。采集基底动脉瘤患者颅内CTA影像DICOM格式数据,应用MIMICS 21.0软件三维重建椎动脉模型,应用3-matic软件对初步获得的模型进行修复,并使用Ansys ICEM软件对模型进行离散化网格划分,最后通过Ansysfluent软件对动脉瘤有限元模型进行数值模拟运算,获得颅内正常动脉与术前、术后动脉瘤部位血流速度、壁切应力、壁压力的分布特征,比较分析正常、术前、术后三种模型之间的血流动力学参数差异。椎动脉阻断前后基底动脉瘤的血流动力学参数存在显著差异,三种模型的血流速度、壁切应力、壁压力分别两两之间差异具有统计学意义(P<0.05)。通过椎动脉阻断的方式,基底动脉瘤的血流动力学发生显著的改变:血流速度下降、壁切应力升高、壁压力下降。

To investigate the hemodynamic changes of basilar aneurysms before and after vertebral artery occlusion. Using Mimics21.0 import case of patients with intracranial aneurysms CTA images DICOM format data, obtain the intracranial aneurysm model, will import the model 3-matic model to build further, Ansys workbench to build a good model for grid division, numerical simulation calculation, the gain of intracranial aneurysm of blood flow velocity, wall pressure and wall shear stress(WSS) values, compare and analyze the hemodynamic parameters of the differences between the three models. There were differences in hemodynamic parameters of basilar aneurysm before and after vertebral artery occlusion, and the differences in blood flow velocity, WSS and wall pressure between the three models were statistically significant(P<0.05). The hemodynamics of basilar aneurysms were significantly altered by vertebral artery occlusion: flow velocity decreased, wall shear stress increased, and wall pressure decreased.