大理地区1022例孕妇产前优生十项检测结果分析

Prenatal TORCH Ten-Item Detection of 1 022 Pregnant Women in the Dali Area

目的:分析大理地区育龄妇女优生十项的检查结果及其临床意义。方法:以2015年1月至2017年12月到大理大学第一附属医院做TORCH筛查的育龄女性为研究对象,收集病原标本1022例,采用酶联免疫吸附法(ELISA)对血清TORCH特异性抗体IgG及IgM进行检测。结果:1022例病原标本中,共有1012例检出抗体阳性,阳性率99.02%,其中HSVⅠIgG、HSVⅡIgG、CMV-IgG、RV-IgG、TOX-IgG阳性率分别是77.10%、11.35%、95.89%、88.45%、14.29%。且联合感染的情况居多,以HSVⅠ+CMV+RV-IgG阳性模式的人数最多,共520例(50.88%)。结论:TORCH血清学指标在大理地区人群中的分布情况主要以IgG阳性居多,鉴于其阳性率较高,该地孕妇TORCH感染的情况有待改善,其次,由于无法判断病人的感染时机以及对新生儿的影响,应该积极开展针对性的检查,做到早预防、早诊断,对母婴健康有一定的现实意义。

Objective:To analyze the results of prenatal TORCH examination in pregnant women and its clinical significance in Dali area. Methods:The pregnant women who took TORCH screening in the First Affiliated Hospital of Dali University from January 2015 to December 2017 were selected as the research subjects, and 1 022 cases of pathogenic specimens were collected. The serum specific antibodies IgG and IgM of TORCH were detected by enzyme linked immunosorbent assay(ELISA). Results:Among these 1 022 pathogenic specimens, 1 012 were positive, with a positive rate of 99.02%. The positive rates of HSV Ⅰ IgG, HSV Ⅱ IgG, CMV-IgG, RV-IgG and TOX-IgG were 77.10%, 11.35%, 95.89%, 88.45% and 14.29%. The incidence of co-infection was the most, and the number of HSVⅠ+CMV+RV-IgG positive cases was the largest, with a total of 520 cases(50.88%). Conclusion:Firstly, the distribution of serological indicators of TORCH in the local population is mainly IgG positive. The situation of TORCH infection needs to be improved in this area because of its high positive rate. Secondly, due to the inability to judge the timing of infection and the impact on the newborns, targeted examinations should be actively carried out, and early prevention and early diagnosis have certain practical significance for maternal and infant health.