逍遥散治疗应激性疾病研究概述

Research overview of Xiaoyao powder in stress diseases

通过对逍遥散临床应用和实验研究的总结发现,逍遥散在治疗应激性疾病方面有较好疗效,应激性刺激作用可以导致头痛、不寐、高血压、焦虑、抑郁、帕金森吞咽障碍等各种疾病,只要辨证准确,逍遥散对这类疾病都有很好的临床疗效。逍遥散对大脑内SP物质、β-内啡肽、色甘酸、5-羟色胺、脑源性神经营养因子、多巴胺、去甲肾上腺素、促肾上腺皮质激素释放激素、精氨酸血管加压素等含量均有调节作用,而且具备调节下丘脑-垂体-肾上腺轴和肾素-血管紧张素-醛固酮系统的作用,随着研究人员对逍遥散的深入研究,其治疗疾病的范围还将扩展。

By summarizing the clinical application and experimental research of Xiaoyao powder,it is found that Xiaoyao powder has a comparatively good therapeutic effect on the treatment of stress diseases. Stress stimulation may lead to headache,insomnia,hypertension,anxiety,depression,Parkinson dysphagia,etc. When the syndrome is accurately differentiated, Xiaoyao powder can have good curative effects on these diseases. Xiaoyao powder has the regulatory function on the content of SP substances in brain,β-endorphin,intal,5-HT,brain-derived neurotrophic factor,dopamine,norepinephrine,corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP). And it also has the regulatory function on the hypothalamic-pituitary-adrenal axis and the renin-angiotensin-aldosterone system (RAAS). With more study on Xiaoyao powder,the scope of its treatment on diseases will be further expanded.