620例结肠黑变病临床资料分析

Analysis of clinical data of 620 cases of melanosis coli

目的探讨分析结肠黑变病(MC)的临床特征、内镜表现及与结直肠癌、结直肠息肉等相关肠道疾病的关系。方法收集2012年10月至2018年12月经宁夏回族自治区人民医院内镜中心行结肠镜检查后诊断的620例MC患者的临床资料、内镜表现及病理诊断结果进行回顾性分析。结果共纳入620例MC患者,其检出人数呈逐年升高趋势,主要以便秘、腹痛为临床表现,主要好发于女性,以>60岁的患者多见,镜下分度以轻度为主,好发于升结肠-直肠,主要合并结直肠息肉、结直肠癌、炎症性肠病、痔疮等,其中合并的结直肠息肉患者中病理结果以腺瘤性息肉多见。结论MC的检出人数呈逐年增长趋势,女性、>60岁的患者多见,主要临床表现为便秘、腹痛,好发升结肠-直肠,以轻度为主,可合并结直肠息肉、结直肠癌、炎症性肠病、痔疮等,可为临床医师提供临床诊断思路。

Objective To investigate the relationship between clinical features,endoscopic findings of MC,colorectal carcinoma,colonic polyps and other related intestinal diseases.Methods The clinical data, endoscopic findings and pathological findings of 620 patients with MC diagnosed by colonoscopy in the endoscopy center of Ningxia Hui Autonomous Region People′s Hospital from 2012- 10 to 2018- 12 were retrospectively analyzed.Results A total of 620 patients with MC were included,and the number of patients detected increases year by year.The main symptoms mainly in women were constipation and abdominal pain. It was more common in patients who over 60 years old,and the microscopic index was mainly light,occured in the ascending colon- rectum mainly combined with colorectal polyps,colorectal cancer,inflammatory bowel disease,hemorrhoids,etc.And patients with colorectal polyps are more common with adenomatous polyps. Conclusion The number of MC detected is increasing year by year.And female patients over 60 years old are more common. The main clinical symptoms are constipation and abdominal pain,occurs mainly light in the ascending colon- rectum that combined with colorectal polyps,colorectal cancer,Inflammatory bowel disease,hemorrhoids.Therefore it can provide clinical diagnostic ideas for clinicians.