放射性肠炎中微血管损伤机制及与内镜表现的关系

The mechanism of microvessel damage and its relationship with endoscopic findings in radiation enteritis

放射性肠炎内镜下常具有黏膜下毛细血管网减少,残留血管异常扩张等较特征性表现。本文主要介绍放射性肠炎中微血管损伤的机制,包括微血管密度下降、黏膜下纤维化、异常新生血管等与内镜下表现的关系,以期为临床治疗放射性肠炎提供新的思路。

Radiation enteritis always showed characteristic decreased capillary network and abnormal dilated vessels at endoscopy.This article mainly reviewed the mechanism of microvessel damage,including the relationship of decreased microvessel density,submucosal fibrosis,abnormal neovascularization with cytokines and inflammatory mediators.These relationships may provide new idea in treatment of radiation enteritis.