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针刺通过调控AMPK-mTOR-细胞自噬改善瘦素抵抗 被引量:1

Acupuncture in Improving Leptin Resistance through Modulation of AMPK-mTOR-Autophagy
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摘要 自噬是细胞内的物质和能量代谢自稳机制。近年来发现自噬与肥胖引起的瘦素抵抗关系密切。本文从AMPK-mTOR-细胞自噬角度诠释针灸治疗单纯性肥胖的机制,以期为针刺减肥的临床应用提供科学依据。 As a homeostatic mechanism of cellular substance and energy metabolism,autophagy has been looked at as a hot topic recently,which has been closely related to leptin resistance caused by obesity.The mechanisms of EA treatment of obesity could be explored from a new perspective,which could provide the theoretical basis for clinical applications of acupuncture treatment of obesity.
作者 李茜 龚美蓉 LI Qian;GONG Meirong(Key Laboratory of Acupuncture and Medicine Research of Ministry ofEducation,Nanjing University of Chinese Medicine,Nanjing 210023,China)
出处 《安徽科技学院学报》 2019年第3期44-47,共4页 Journal of Anhui Science and Technology University
基金 江苏省自然科学基金(BK20181420)
关键词 针刺 瘦素抵抗 自噬 AMPK-mTOR通路 Acupuncture Leptin resistance Autophagy AMPK-mTOR signaling pathway
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